We performed a meta-analysis to synthesize evidence on the efficacy and safety of physical
exercise as an add-on therapeutic intervention for quality of life (QoL), depressive symptoms …

The relationship of cortical structure and specific neuronal circuitry to global brain function,
particularly its perturbations related to the development and progression of neuropathology …

The brain is constituted of multiple networks of functionally correlated brain areas, out of
which the default-mode network (DMN) is the largest. Most existing research into the DMN …

Human brains lie at the core of complex neurobiological systems, where the neurons,
circuits, and subsystems interact in enigmatic ways. Understanding the structural and …

The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

Resting-state (RS) functional magnetic resonance (MR) imaging constitutes a novel
paradigm that examines spontaneous brain function by using blood oxygen level …

Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …

The purpose of this work was to evaluate changes in the connectivity patterns of a set of
cognitively relevant, dynamically interrelated brain networks in association with cognitive …

Background Cognitive impairment is a common non-motor symptom in Parkinson's disease.
So far, the underlying pathophysiology remains unclear. Several alterations in functional …