Transposable elements (TEs) are mobile DNA sequences that propagate within genomes.
Through diverse invasion strategies, TEs have come to occupy a substantial fraction of …

Transposable elements and retroviruses are found in most genomes, can be pathogenic
and are widely used as gene-delivery and functional genomics tools. Exploring whether …

Transposable elements (TEs) comprise a major portion of many plant genomes and bursts
of TE movements cause novel genomic variation within species. In order to maintain proper …

The integration of a DNA copy of the viral RNA genome into host chromatin is the defining
step of retroviral replication. This enzymatic process is catalyzed by the virus-encoded …

During both embryonic development and adult tissue regeneration, changes in chromatin
structure driven by master transcription factors lead to stimulus-responsive transcriptional …

Here, we report the design, construction, and characterization of a tRNA neochromosome, a
designer chromosome that functions as an additional, de novo counterpart to the native …

RNA synthesis in eukaryotes is divided among three RNA polymerases (RNAPs). RNAP III
transcribes hundreds of tRNA genes and fewer additional short RNA genes. We survey …

Plants maintain extensive growth flexibility under different environmental conditions,
allowing them to continuously and rapidly adapt to alterations in their environment. A large …

RNA polymerase III (RNAPIII) synthesizes essential and abundant noncoding RNAs such as
transfer RNAs. Controlling RNAPIII span of activity by accurate and efficient termination is a …

Transcription of tRNA genes by RNA polymerase III (RNAPIII) is tuned by signaling
cascades. The emerging notion of differential tRNA gene regulation implies the existence of …