NAD (H) and NADP (H) are essential co-enzymes which dominantly control a number of
fundamental biological processes by acting as reducing power and maintaining the …

Abstract Calcium ion (Ca2+) is a multifaceted signaling molecule that acts as an important
second messenger. During the course of evolution, plants and animals have developed …

Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial
arrhythmogenic syndrome characterized by sudden death. There are several genetic forms …

Calcium (Ca2+) signaling and nicotinamide adenine dinucleotide (NAD) signaling are two
basic signal regulation pathways in organisms, playing crucial roles in signal transduction …

Abstract Calcium (Ca 2+) signaling represents a universal information code in plants,
playing crucial roles spanning developmental processes to stress responses. Ca 2+ signals …

Calmodulin (CaM) is a highly-expressed Ca 2+ binding protein known to bind hundreds of
protein targets. Its binding selectivity to many of these targets is partially attributed to the …

Calmodulin (CaM) serves as an important Ca2+ signaling hub that regulates many protein
signaling pathways. Recently, it was demonstrated that plant CaM homologues can regulate …

Calcineurin, also known as protein phosphatase 2B, is a heterodimeric serine threonine
phosphatase involved in numerous signaling pathways. During the past 50 years …

Calmodulin (CaM) is a universal Ca2+ binding protein known to bind at least 300 targets.
The selectivity and specificity towards these targets are partially attributed to the protein's …

Cellular calcium either directly controls, or at a minimum modulates nearly, if not, all human
functions. As such, the structural motif that forms the calcium binding pocket (EF-hand) is …