Selenium and selenoproteins in health

F Zhang, X Li, Y Wei - Biomolecules, 2023 - mdpi.com
Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …

[HTML][HTML] Deiodinases control local cellular and systemic thyroid hormone availability

J Köhrle, C Frädrich - Free Radical Biology and Medicine, 2022 - Elsevier
Iodothyronine deiodinases (DIO) are a family of selenoproteins controlling systemic and
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …

Selenium and selenoproteins in adipose tissue physiology and obesity

AA Tinkov, OP Ajsuvakova, T Filippini, JC Zhou, XG Lei… - Biomolecules, 2020 - mdpi.com
Selenium (Se) homeostasis is tightly related to carbohydrate and lipid metabolism, but its
possible roles in obesity development and in adipocyte metabolism are unclear. The …

Cardiac autonomic neuropathy: a progressive consequence of chronic low-grade inflammation in type 2 diabetes and related metabolic disorders

NMZ Bakkar, HS Dwaib, S Fares, AH Eid… - International journal of …, 2020 - mdpi.com
Cardiac autonomic neuropathy (CAN) is one of the earliest complications of type 2 diabetes
(T2D), presenting a silent cause of cardiovascular morbidity and mortality. Recent research …

[HTML][HTML] Selenium, as selenite, prevents adipogenesis by modulating selenoproteins gene expression and oxidative stress–related genes

NFA El-Magd, PO Barbosa, J Nick, V Covalero… - Nutrition, 2022 - Elsevier
Objectives The aim of this study was to assess the effect of the micronutrient selenium, as
inorganic selenite, on adipocytes differentiation, and to identify underlying molecular …

Selenium status and type 2 diabetes risk

YC Huang, GF Combs Jr, TL Wu, H Zeng… - Archives of biochemistry …, 2022 - Elsevier
Optimal selenium (Se) status is necessary for overall health. That status can be affected by
food intake pattern, age, sex, and health status. At nutritional levels of intake, Se functions …

Emerging functions of adipokines in linking the development of obesity and cardiovascular diseases

X Su, D Peng - Molecular Biology Reports, 2020 - Springer
Increasing evidence shows that obesity is the critical factor in shaping cardio-metabolic
phenotypes. However, the pathogenic mechanisms remain incompletely clarified. According …

[HTML][HTML] Beneficial metabolic effects of chitosan and chitosan oligosaccharide on epididymal WAT browning and thermogenesis in obese rats

J Wang, W He, D Yang, H Cao, Y Bai, J Guo, Z Su - Molecules, 2019 - mdpi.com
Many anti-obesity chemicals have been withdrawn from the market due to serious adverse
reactions, and the researchers have turned their attention to low-toxic natural products …

[HTML][HTML] Effect of exercise on peritoneal microenvironment and progression of ovarian cancer

MJ Morrisson, F Bi, K Yang, SL Cady… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Ovarian cancer is one of the deadliest gynecological malignancies and lacks treatments that
do not significantly impact patient health-related quality of life. Exercise has been associated …

Endoplasmic reticulum-resident selenoproteins and their roles in glucose and lipid metabolic disorders

Z Shi, Z Han, J Chen, JC Zhou - … et Biophysica Acta (BBA)-Molecular Basis …, 2024 - Elsevier
Glucose and lipid metabolic disorders (GLMDs), such as diabetes, dyslipidemia, metabolic
syndrome, nonalcoholic fatty liver disease, and obesity, are significant public health issues …