High-density lipoproteins (HDLs) represent a family of particle characterized by the
presence of apolipoprotein AI (apoA-I) and by their ability to transport cholesterol from …

Lipoproteins were initially defined according to their composition (lipids and proteins) and
classified according to their density (from very low-to high-density lipoproteins—HDLs) …

Background: The high-density lipoprotein hypothesis of atherosclerosis has been
challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors, which …

Sepsis is a major health issue with mortality exceeding 30% and few treatment options. We
found that high-density lipoprotein cholesterol (HDL-C) abundance was reduced by 45% in …

Rationale: High-density lipoprotein (HDL) cholesterol (HDL-C) levels decline during sepsis,
and lower levels are associated with worse survival. However, the genetic mechanisms …

High-density lipoproteins (HDLs) are a class of blood particles, principally involved in
mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches …

The main role of cholesteryl ester transfer protein (CETP) is the transfer of cholesteryl esters
and triglycerides between high-density lipoprotein (HDL) particles and triglyceride-rich …

Sepsis, defined as the dysregulated immune response to an infection leading to organ
dysfunction, is one of the leading causes of mortality around the globe. Despite the …

OBJECTIVE: To ascertain the association between cholesterol and triglyceride levels on ICU
admission and mortality in patients with sepsis. DATA SOURCES: Systematic review and …

Objectives Changes in lipid profiles occur in systemic inflammatory response syndrome
(SIRS), whether due to sepsis or another cause. Hypocholesterolemia associated with …