MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …

Macrophage scavenger receptor 1 (MSR1), also named CD204, holds key inflammatory
roles in multiple pathophysiologic processes. Present primarily on the surface of various …

Hundreds of microRNAs (miRNAs) are expressed in distinct spatial and temporal patterns
during embryonic and postnatal mouse development. The loss of all miRNAs through the …

Multi-pathway approaches for the treatment of complex polygenic disorders are emerging as
alternatives to classical monotarget therapies and microRNAs are of particular interest in …

Recent investigations revealed that macrophages could be trained with an altered
responsiveness, raising the possibility of combating autoimmune diseases by imparting anti …

Summary microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly
downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients …

The insulin signaling pathway is composed of a large number of molecules that positively or
negatively modulate insulin specific signal transduction following its binding to the cognate …

Regular physical exercise has been recognized as a potent modulator of immune function,
with its effects including enhanced immune surveillance, reduced inflammation, and …

MicroRNAs (miRNAs) play a key role in fine-tuning host immune homeostasis and
responses through the negative regulation of mRNA stability and translation. The pathways …

It is widely accepted that the pathophysiology and treatment of myalgic encephalomyelitis/
chronic fatigue syndrome (ME/CFS) could be considerably improved. The heterogeneity of …