Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence

B Salehi, C Quispe, I Chamkhi, N El Omari… - Frontiers in …, 2021 - frontiersin.org
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

Chalcone synthesis, properties and medicinal applications: a review

A Rammohan, JS Reddy, G Sravya, CN Rao… - Environmental …, 2020 - Springer
Chalcone is an aromatic ketone that forms the central core of many important biological
compounds, which are known as chalcones. Chalcones are the biogenetic precursors of …

Naturally occurring chalcones and their biological activities

Z Rozmer, P Perjési - Phytochemistry reviews, 2016 - Springer
The aim of this review is to summarize the various naturally occurring chalcone compounds
which have been isolated from different plants. Chalcones considered as obligate …

Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used …

LG Ranilla, YI Kwon, E Apostolidis, K Shetty - Bioresource technology, 2010 - Elsevier
Traditionally used medicinal plants, herbs and spices in Latin America were investigated to
determine their phenolic profiles, antioxidant activity and in vitro inhibitory potential against …

Synthesis and pharmacological properties of chalcones: a review

SL Gaonkar, UN Vignesh - Research on chemical intermediates, 2017 - Springer
Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …

A review of anti-infective and anti-inflammatory chalcones

Z Nowakowska - European journal of medicinal chemistry, 2007 - Elsevier
Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in
edible plants, and have also been shown to display a diverse array of pharmacological …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Natural product based leads to fight against leishmaniasis

N Singh, BB Mishra, S Bajpai, RK Singh… - Bioorganic & medicinal …, 2014 - Elsevier
The growing incidence of parasitic resistance against generic pentavalent antimonials,
specifically for visceral disease in Indian subcontinent, is a serious issue in Leishmania …

Synthesis of chalcone analogues with increased antileishmanial activity

P Boeck, CAB Falcão, PC Leal, RA Yunes… - Bioorganic & medicinal …, 2006 - Elsevier
Eighteen analogues of an active natural chalcone were synthesized using xanthoxyline and
some derivatives, and these analogues were tested for selective activity against both …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …