BACKGROUND A gap exists between in vivo and ex vivo coagulation when investigated by
use of the coagulation tests prothrombin time (PT) and activated partial thromboplastin time …

Heparin has been recognized as a valuable anticoagulant and antithrombotic for several
decades and is still widely used in clinical practice for a variety of indications. The …

BACKGROUND & AIMS: Patients with cirrhosis have an increased tendency to develop
thromboses despite the longer coagulation times of their plasma, compared with that of …

The role played by coagulation defects in the occurrence of bleeding in cirrhosis is still
unclear. This is partly due to the lack of tests that truly reflect the balance of procoagulant …

Patients with cerebral small vessel disease (SVD) can present as isolated lacunar infarction
or with diffuse white matter changes, with the imaging appearance of leukoaraiosis …

Endothelial microparticles (EMP) are small vesicles released from disturbed endothelial
cells (EC). Owing to the central importance of EC injury in thrombotic and inflammatory …

Statistical analysis of evolutionary-related protein sequences provides information about
their structure, function, and history. We show that Restricted Boltzmann Machines (RBM) …

The molecular basis for the anticoagulant action of heparin lies in its ability to bind to and
enhance the inhibitory activity of the plasma protein antithrombin against several serine …

Heterocyclic N-oxides have emerged as potent compounds with anticancer, antibacterial,
antihypertensive, antiparasitic, anti-HIV, anti-inflammatory, herbicidal, neuroprotective, and …

As activation of the coagulation pathway is a physiological response to injury, the
development of disseminated intravascular coagulation (DIC) is a warning signal to the …