Affinity‐based drug delivery systems utilize interactions between the therapeutic drug and
the delivery system to manipulate drug loading and to control drug release. In this paper …

Immunotherapy is a rapidly developing area of cancer treatment due to its higher specificity
and potential for greater efficacy than traditional therapies. Immune cell modulation through …

Magnetic core–shell nanocarriers have been attracting growing interest owing to their
physicochemical and structural properties. The main principles of magnetic nanoparticles …

To improve transfection efficiency and reduce the cytotoxicity of polymeric gene vectors,
reducible polycations (RPC) were synthesized from low molecular weight (MW) branched …

End-functionalized poly (N-isopropylacrylamide)(PNIPA) was synthesized by living free
radical polymerization and conventional free radical polymerization and was used to …

This paper reports the disassembly of layer-by-layer (LbL) films of plasmid DNA and a
reducible cationic polypeptide. To utilize a reducing microenvironment of cellular plasma …

Controlled intracellular disassembly of polyelectrolyte complexes of polycations and DNA
(polyplexes) is a crucial step for the success of nonviral gene delivery. Motivated by our …

The DNA release dynamics of bioreducible poly (amido amine) polyplexes were studied in
real time by atomic force microscopy (AFM). DNA release is triggered by a depolymerization …

Nanosystems have unique physical and biological properties. Various systems have been
designed for medical use and offer promising ways of delivering drugs at high …

Drug delivery systems (DDSs) have been developed to target tumor cells by releasing active
biomolecules at the specific site of infection, thus eliminating the side effects of anticancer …