Acidocalcisomes? Conserved from bacteria to man

R Docampo, W de Souza, K Miranda… - Nature Reviews …, 2005 - nature.com
Recent work has shown that acidocalcisomes, which are electron-dense acidic organelles
rich in calcium and polyphosphate, are the only organelles that have been conserved during …

[PDF][PDF] The malaria digestive vacuole

J Wunderlich, P Rohrbach, JP Dalton - Front. Biosci, 2012 - researchgate.net
Introduction 3. Structure and formation of the DV 4. Hemoglobin digestion 5. Ion
homeostasis 5.1. pH homeostasis 5.2. Calcium homeostasis 6. Transporters in the DV …

Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites.

CT Hotta, ML Gazarini, FH Beraldo, FP Varotti… - Nature cell …, 2000 - nature.com
* Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, São
Paulo 05508-90, Brasil† Dipartimento di Scienze Biomediche Sperimentali, Centro CNR …

Cyclic AMP and calcium interplay as second messengers in melatonin-dependent regulation of Plasmodium falciparum cell cycle

FH Beraldo, FM Almeida, AM da Silva… - The Journal of cell …, 2005 - rupress.org
The host hormone melatonin increases cytoplasmic Ca2+ concentration and synchronizes
Plasmodium cell cycle (Hotta, CT, ML Gazarini, FH Beraldo, FP Varotti, C. Lopes, RP …

Antimalarial Quinolines and Artemisinin Inhibit Endocytosis in Plasmodium falciparum

HC Hoppe, DA van Schalkwyk… - Antimicrobial agents …, 2004 - Am Soc Microbiol
Endocytosis is a fundamental process of eukaryotic cells and fulfills numerous functions,
most notably, that of macromolecular nutrient uptake. Malaria parasites invade red blood …

Acidocalcisomes and a vacuolar H+-pyrophosphatase in malaria parasites

N Marchesini, S Luo, CO Rodrigues… - Biochemical …, 2000 - portlandpress.com
Plasmodium berghei trophozoites were loaded with the fluorescent calcium indicator, fura-2
acetoxymethyl ester, to measure their intracellular Ca2+ concentration ([Ca2+] i).[Ca2+] i …

Quantitative calcium measurements in subcellular compartments of Plasmodium falciparum-infected erythrocytes

P Rohrbach, O Friedrich, J Hentschel, H Plattner… - Journal of Biological …, 2005 - ASBMB
The acidic food vacuole exerts several important functions during intraerythrocytic
development of the human malarial parasite Plasmodium falciparum. Hemoglobin taken up …

Membrane transport in the malaria parasite and its host erythrocyte

K Kirk, AM Lehane - Biochemical Journal, 2014 - portlandpress.com
As it grows and replicates within the erythrocytes of its host the malaria parasite takes up
nutrients from the extracellular medium, exports metabolites and maintains a tight control …

Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro

SP Maher, A Vantaux, V Chaumeau, ACY Chua… - Scientific Reports, 2021 - nature.com
Improved control of Plasmodium vivax malaria can be achieved with the discovery of new
antimalarials with radical cure efficacy, including prevention of relapse caused by …

Calcium regulation in the intraerythrocytic malaria parasite Plasmodium falciparum

LM Alleva, K Kirk - Molecular and biochemical parasitology, 2001 - Elsevier
The regulation of intracellular Ca2+ in the intraerythrocytic form of the human malaria
parasite, Plasmodium falciparum, was investigated using parasites 'isolated'from their host …