Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

Function and mechanism of histone β-hydroxybutyrylation in health and disease

T Zhou, X Cheng, Y He, Y Xie, F Xu, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Histone post-translational modifications (HPTMs) are essential epigenetic mechanisms that
affect chromatin-associated nuclear processes without altering the DNA sequence. With the …

Long noncoding RNAs: novel insights into gastric cancer

X Fang, H Pan, R Leng, D Ye - Cancer letters, 2015 - Elsevier
Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides. Recent
advances in the non-protein coding part of human genome analysis have discovered …

The impact of epigenetics on cardiovascular disease

D Prasher, SC Greenway… - Biochemistry and Cell …, 2020 - cdnsciencepub.com
Mortality and morbidity from cardiovascular diseases (CVDs) represents a huge burden to
society. It is recognized that environmental factors and individual lifestyles play important …

The regulation and function of histone crotonylation

A Ntorla, JR Burgoyne - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Histone crotonylation is a newly identified epigenetic modification that has a pronounced
ability to regulate gene expression. It belongs to an expanding group of short chain lysine …

[HTML][HTML] Atherosclerosis and cancer; a resemblance with far-reaching implications

JV Tapia-Vieyra, B Delgado-Coello… - Archives of medical …, 2017 - Elsevier
Atherosclerosis and cancer are chronic diseases considered two of the main causes of
death all over the world. Taking into account that both diseases are multifactorial, they share …

The role of epigenetics in genetic and environmental epidemiology

C Ladd-Acosta, MD Fallin - Epigenomics, 2016 - Taylor & Francis
Epidemiology is the branch of science that investigates the causes and distribution of
disease in populations in order to provide preventative measures and promote human …

Guidelines for pre-analytical conditions for assessing the methylation of circulating cell-free DNA

MA Kerachian, M Azghandi, S Mozaffari-Jovin… - Clinical …, 2021 - Springer
Methylation analysis of circulating cell-free DNA (cirDNA), as a liquid biopsy, has a
significant potential to advance the detection, prognosis, and treatment of cancer, as well as …

Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the …

C Perrino, AL Barabási, G Condorelli… - Cardiovascular …, 2017 - academic.oup.com
Despite advances in myocardial reperfusion therapies, acute myocardial
ischaemia/reperfusion injury and consequent ischaemic heart failure represent the number …

Nutrigenomics, the microbiome, and gene-environment interactions: new directions in cardiovascular disease research, prevention, and treatment: a scientific …

JF Ferguson, H Allayee, RE Gerszten… - Circulation …, 2016 - Am Heart Assoc
Cardiometabolic diseases are the leading cause of death worldwide and are strongly linked
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …