[HTML][HTML] Updated diagnostic criteria and classification of mast cell disorders: a consensus proposal

P Valent, C Akin, K Hartmann, I Alvarez-Twose… - …, 2021 - journals.lww.com
Mastocytosis is a hematologic neoplasm characterized by expansion and focal
accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone …

The pathophysiology of anaphylaxis

LL Reber, JD Hernandez, SJ Galli - Journal of Allergy and Clinical …, 2017 - Elsevier
Anaphylaxis is a severe systemic hypersensitivity reaction that is rapid in onset;
characterized by life-threatening airway, breathing, and/or circulatory problems; and usually …

Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis

G Greiner, B Sprinzl, A Górska… - Blood, The Journal …, 2021 - ashpublications.org
Mastocytosis is a hematopoietic neoplasm characterized by expansion of KIT D816V-
mutated clonal mast cells in various organs and severe or even life-threatening anaphylactic …

New insights into the pathogenesis of mastocytosis: emerging concepts in diagnosis and therapy

P Valent, C Akin, WR Sperr, HP Horny… - Annual Review of …, 2023 - annualreviews.org
Mastocytosis is a heterogeneous group of neoplasms defined by a numerical increase and
accumulation of clonal mast cells (MCs) in various organ systems. The disease may present …

The ingenious mast cell: Contemporary insights into mast cell behavior and function

JS Dahlin, M Maurer, DD Metcalfe, G Pejler… - Allergy, 2022 - Wiley Online Library
Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …

Urticaria and angioedema: an update on classification and pathogenesis

S Radonjic-Hoesli, KS Hofmeier, S Micaletto… - Clinical reviews in …, 2018 - Springer
Urticaria is a common, mast cell-driven disease presenting with wheals or angioedema or
both. In the last years, urticaria has increasingly attracted notice to clinicians and …

New developments in diagnosis, prognostication, and treatment of advanced systemic mastocytosis

A Reiter, TI George, J Gotlib - … Journal of the American Society of …, 2020 - ashpublications.org
Systemic mastocytosis (SM) has greatly benefited from the broad application of precision
medicine techniques to hematolymphoid neoplasms. Sensitive detection of the recurrent KIT …

Mast cell activation syndromes: collegium internationale allergologicum update 2022

P Valent, K Hartmann, P Bonadonna… - International archives of …, 2022 - karger.com
Mast cell activation syndromes (MCASs) are defined by systemic severe and recurrent mast
cell activation, usually in form of anaphylaxis, a substantial, event-related increase of the …

[HTML][HTML] Personalized management strategies in mast cell disorders: ECNM-AIM user's guide for daily clinical practice

P Valent, K Hartmann, J Schwaab… - The Journal of Allergy …, 2022 - Elsevier
Mastocytosis is a myeloid neoplasm defined by expansion and focal accumulation of clonal
mast cells (MCs) in one or more organs. The disease exhibits a complex pathology and may …

[HTML][HTML] Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions

P Valent, A Orazi, MR Savona, MM Patnaik… - …, 2019 - ncbi.nlm.nih.gov
Chronic myelomonocytic leukemia (CMML) is a myeloid neoplasm characterized by
dysplasia, abnormal production and accumulation of monocytic cells and an elevated risk of …