Glaucoma as a neurodegenerative disease
Glaucoma as a neurodegenerative disease is a valid working hypothesis to understand
neural injury in the visual system. This paradigm may stimulate the discovery of innovative …
neural injury in the visual system. This paradigm may stimulate the discovery of innovative …
Risk factors and open-angle glaucoma: classification and application
MV Boland, HA Quigley - Journal of glaucoma, 2007 - journals.lww.com
Decades of epidemiologic research into open-angle glaucoma have elucidated several risk
factors related in some way to the disease. As more and more risk factors are identified …
factors related in some way to the disease. As more and more risk factors are identified …
APOE distribution in world populations with new data from India and the UK
PP Singh, M Singh, SS Mastana - Annals of human biology, 2006 - Taylor & Francis
Background: The APOE gene and its protein product is associated with a number of plasma
proteins like very-low density lipoprotein (VLDL), high density lipoprotein (HDL) …
proteins like very-low density lipoprotein (VLDL), high density lipoprotein (HDL) …
The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology
SF Janssen, TGMF Gorgels, WD Ramdas… - Progress in retinal and …, 2013 - Elsevier
Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
The genetics of primary open-angle glaucoma: a review
RR Allingham, Y Liu, DJ Rhee - Experimental eye research, 2009 - Elsevier
Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …
High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease
H Tamura, H Kawakami, T Kanamoto, T Kato… - Journal of the …, 2006 - Elsevier
The clinical and genetic relationships between Alzheimer's disease (AD) and glaucoma
remain obscure. The aim of this study was to determine the prevalence of open-angle …
remain obscure. The aim of this study was to determine the prevalence of open-angle …
A sick eye in a sick body? Systemic findings in patients with primary open-angle glaucoma
M Pache, J Flammer - Survey of ophthalmology, 2006 - Elsevier
Despite intense research, the pathogenesis of primary open-angle glaucoma (POAG) is still
not completely understood. There is ample evidence for a pathophysiological role of …
not completely understood. There is ample evidence for a pathophysiological role of …
Alzheimer's disease and retinal neurodegeneration
L Guo, J Duggan, MF Cordeiro - Current Alzheimer Research, 2010 - ingentaconnect.com
Alzheimer's disease (AD) is the major cause of dementia in the world. Although the
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …
entorhinal cortex and hippocampal complex are best known as the sites of early pathology …
Genetic dissection of myocilin glaucoma
G Gong, O Kosoko-Lasaki, GR Haynatzki… - Human molecular …, 2004 - academic.oup.com
Primary open-angle glaucoma (POAG) is a complex disease with unknown causes.
However, in the past decade, POAG has been linked to six chromosomal regions, of which …
However, in the past decade, POAG has been linked to six chromosomal regions, of which …
Visual contrast sensitivity in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints
Deficits in contrast sensitivity (CS) have been reported in Alzheimer's disease (AD).
However, the extent of these deficits in prodromal AD stages, including mild cognitive …
However, the extent of these deficits in prodromal AD stages, including mild cognitive …