Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Recent strategies to improve boron dipyrromethene (BODIPY) for photodynamic cancer therapy: an updated review

CS Kue, SY Ng, SH Voon, A Kamkaew… - Photochemical & …, 2018 - Springer
BODIPYs are photosensitizers activatable by light to generate highly reactive singlet oxygen
(1 O 2) from molecular oxygen, leading to tissue damage in the photoirradiated region …

Ultralow-power near infrared lamp light operable targeted organic nanoparticle photodynamic therapy

L Huang, Z Li, Y Zhao, Y Zhang, S Wu… - Journal of the …, 2016 - ACS Publications
Tissue penetration depth is a major challenge in practical photodynamic therapy (PDT). A
biocompatible and highly effective near infrared (NIR)-light-absorbing carbazole-substituted …

2D transition metal dichalcogenide nanosheets for photo/thermo-based tumor imaging and therapy

H Chen, T Liu, Z Su, L Shang, G Wei - Nanoscale horizons, 2018 - pubs.rsc.org
Two-dimensional (2D) graphene-like nanomaterials show wide applications in the fields of
nanodevices, sensors, energy materials, catalysis, drug delivery, bioimaging, and tissue …

Photodynamic therapy based on organic small molecular fluorescent dyes

L Li, Y Chen, W Chen, Y Tan, H Chen, J Yin - Chinese Chemical Letters, 2019 - Elsevier
Photodynamic therapy (PDT) has shown promise as an effective treatment modality for
cancer and other localized diseases due to its noninvasive properties and spatiotemporal …

Small molecules for active targeting in cancer

CS Kue, A Kamkaew, K Burgess… - Medicinal research …, 2016 - Wiley Online Library
For the purpose of this review, active targeting in cancer research encompasses strategies
wherein a ligand for a cell surface receptor expressed on tumor cells is used to deliver a …

BODIPYs in PDT: a journey through the most interesting molecules produced in the last 10 years

MC Malacarne, MB Gariboldi, E Caruso - International Journal of …, 2022 - mdpi.com
Over the past 30 years, photodynamic therapy (PDT) has shown great development. In the
clinical setting the few approved molecules belong almost exclusively to the porphyrin …

Nanoparticles as theranostic vehicles in experimental and clinical applications—focus on prostate and breast cancer

J Elgqvist - International journal of molecular sciences, 2017 - mdpi.com
Prostate and breast cancer are the second most and most commonly diagnosed cancer in
men and women worldwide, respectively. The American Cancer Society estimates that …

A simple, yet multifunctional, nanoformulation for eradicating tumors and preventing recurrence with safely low administration dose

Y Liu, Y Xu, Z Zhang, Y Huo, D Chen, W Ma, K Sun… - Nano Letters, 2019 - ACS Publications
Designing simple-structured nanomedicine without lacking key functionalities, thereby
avoiding incomplete damage or relapse of tumor with the administration of a safe dose, is …

Chitosan-coated poly (lactic-co-glycolic acid)-diiodinated boron-dipyrromethene nanoparticles improve tumor selectivity and stealth properties in photodynamic …

SH Voon, SX Tiew, CS Kue, HB Lee… - Journal of …, 2016 - ingentaconnect.com
Their limited solubility and lack of tumor selectivity limit the clinical usefulness of
photosensitizers. Various nanostructures have been evaluated as delivery agents for …