Deciphering the recent trends in pesticide bioremediation using genome editing and multi-omics approaches: A review

S Hassan, BA Ganai - World Journal of Microbiology and Biotechnology, 2023 - Springer
Pesticide pollution in recent times has emerged as a grave environmental problem
contaminating both aquatic and terrestrial ecosystems owing to their widespread use …

[HTML][HTML] Revolutionizing biofuel generation: Unleashing the power of CRISPR-Cas mediated gene editing of extremophiles

D Garg, MK Samota, N Kontis, N Patel, S Bala… - Microbiological …, 2023 - Elsevier
Molecular biology techniques like gene editing have altered the specific genes in micro-
organisms to increase their efficiency to produce biofuels. This review paper investigates the …

Multiplex CRISPR-Cas9 gene-editing can deliver potato cultivars with reduced browning and acrylamide

DNP Ly, S Iqbal, J Fosu-Nyarko, S Milroy, MGK Jones - Plants, 2023 - mdpi.com
Storing potato tubers at cold temperatures, either for transport or continuity of supply, is
associated with the conversion of sucrose to reducing sugars. When cold-stored cut tubers …

Enteric neuropathy in diabetes: Implications for gastrointestinal function

MMI Abdalla - World Journal of Gastroenterology, 2024 - pmc.ncbi.nlm.nih.gov
Diabetes, commonly known for its metabolic effects, also critically affects the enteric nervous
system (ENS), which is essential in regulating gastrointestinal (GI) motility, secretion, and …

CRISPR technologies in Chinese hamster ovary cell line engineering

K Glinšek, K Bozovičar, T Bratkovič - International journal of molecular …, 2023 - mdpi.com
The Chinese hamster ovary (CHO) cell line is a well-established platform for the production
of biopharmaceuticals due to its ability to express complex therapeutic proteins with human …

[HTML][HTML] Advancing diabetes management: Exploring pancreatic beta-cell restoration's potential and challenges

MMI Abdalla - World Journal of Gastroenterology, 2024 - pmc.ncbi.nlm.nih.gov
Diabetes mellitus, characterized by chronic hyperglycemia due to insulin deficiency or
resistance, poses a significant global health burden. Central to its pathogenesis is the …

Untangling the Context-Specificity of Essential Genes by Means of Machine Learning: A Constructive Experience

M Giordano, E Falbo, L Maddalena, M Piccirillo… - Biomolecules, 2023 - mdpi.com
Gene essentiality is a genetic concept crucial for a comprehensive understanding of life and
evolution. In the last decade, many essential genes (EGs) have been determined using …

CES1‐Triggered Liver‐Specific Cargo Release of CRISPR/Cas9 Elements by Cationic Triadic Copolymeric Nanoparticles Targeting Gene Editing of PCSK9 for …

Y Zhao, Y Li, F Wang, X Gan, T Zheng… - Advanced …, 2023 - Wiley Online Library
The broad application of clustered regularly interspaced short palindromic repeat
(CRISPR)/Cas9 genome editing tools is hindered by challenges in the efficient delivery of its …

Targeting the Depletion of M2 Macrophages: Implication in Cancer Immunotherapy

T Festekdjian, B Bonavida - Critical Reviews™ in Oncogenesis, 2024 - dl.begellhouse.com
We have witnessed the emergence of immunotherapy against various cancers that resulted
in significant clinical responses and particularly in cancers that were resistant to …

CRISPR-Cas9 as a potential cancer therapy agent: An update

S Sadr, PA Simab, H Borji - Research in Biotechnology and …, 2023 - rbes.rovedar.com
Cancer is the second leading cause of death globally and remains a major economic and
social burden. Although our understanding of cancer at the molecular level continues to …