[HTML][HTML] Current naturopathy to combat Alzheimer's disease

A Chakrovorty, B Bhattacharjee, A Saxena… - Current …, 2023 - ncbi.nlm.nih.gov
Neurodegeneration is the progressive loss of structure or function of neurons, which may
ultimately involve cell death. The most common neurodegenerative disorder in the brain …

Delivery of apoplastic extracellular vesicles encapsulating green-synthesized silver nanoparticles to treat citrus canker

I Gaurav, A Thakur, G Kumar, Q Long, K Zhang… - Nanomaterials, 2023 - mdpi.com
The citrus canker pathogen Xanthomonas axonopodis has caused severe damage to citrus
crops worldwide, resulting in significant economic losses for the citrus industry. To address …

Phytochemicals as therapeutic interventions in neurodegenerative diseases

RV Kavitha, JR Kumar, C Egbuna, JC Ifemeje - Phytochemicals as lead …, 2020 - Elsevier
Neurological disorders are ranked as a leading disorder under the subgroup of disability-
adjusted life years (DALYs) in 2015 under the global burden of diseases and second …

Pharmacokinetics and brain penetration study of chlorogenic acid in rats

G Kumar, P Paliwal, S Mukherjee, N Patnaik… - Xenobiotica, 2019 - Taylor & Francis
The present study is designed to investigate the brain distribution and plasma
pharmacokinetics profiles of chlorogenic acid (CGA) after intranasal administration in …

Inhibition of Gelatinases (MMP-2 and MMP-9) by Withania somnifera Phytochemicals Confers Neuroprotection in Stroke: An In Silico Analysis

G Kumar, R Patnaik - Interdisciplinary Sciences: Computational Life …, 2018 - Springer
A stroke or cerebrovascular accident is a serious, life-threatening medical condition that
occurs when the blood supply to part of the brain is severely reduced or cut off, depriving …

Synthesis, in-vitro and in-silico evaluation of silver nanoparticles with root extract of Withania somnifera for antibacterial activity via binding of penicillin-binding protein …

I Gaurav, T Singh, A Thakur, G Kumar… - Current …, 2020 - ingentaconnect.com
Background: Metal Nanoparticles (NPs) have been widely used for various applications in
biomedical sciences, including in drug delivery, and as therapeutic agents, but limited owing …

Withania somnifera phytochemicals confer neuroprotection by selective inhibition of nNos: An in silico study to search potent and selective inhibitors for human …

G Kumar, P Paliwal, N Patnaik… - Journal of Theoretical and …, 2017 - World Scientific
Neuronal nitric oxide synthase (nNOS or NOS1) is an important therapeutic target for the
treatment of various neurological diseases. A major challenge faced in the design of nNOS …

Identification of potential inhibitors of PARP-1, a regulator of caspase-independent cell death pathway, from Withania somnifera phytochemicals for combating neurotoxicity: A …

S Mukherjee, G Kumar, R Patnaik - Journal of Theoretical and …, 2017 - World Scientific
Poly (ADP-ribose) polymerase-1 (PARP-1) reverses DNA damage by repairing DNA nicks
and breaks in the normal cellular environment. However, during abnormal conditions like …

GC-MS and HPLC analyses of phytochemical compounds from Withania somnifera L. leaves extract

M El-Hefny, A El-Kareem, SM Mamoun… - Alexandria Journal of …, 2022 - journals.ekb.eg
In the present work, the shrub W. somnifera was used as a source for the extraction of
bioactive molecules. Leaves were extracted by ethanol and analyzed by Gas …

Neuroprotective effects of steroids

MS Refaey, MA Shah, MAA Fayed, A Rasul… - Phytonutrients and …, 2023 - Elsevier
Neurodegenerative diseases are one of the most predominant diseases in this century. This
concept has been used to characterize several disorders caused by gradual loss of normal …