Enaminones are well known as platform building blocks in organic synthesis. It can be
transformed in the form of diverse cascade reactions to build new chemical bonds by means …

Aplysiasecosterol A (1) is a structurally unusual 9, 11-secosteroid isolated from the sea hare
Aplysia kurodai. We have accomplished the first and asymmetric total synthesis of 1 in a …

A Ni‐catalyzed halogenation of enol triflates was developed and it enables the synthesis of
a broad range of alkenyl iodides, bromides, and chlorides under mild reaction conditions …

The first total syntheses of aflavazole (6) and 14-hydroxyaflavinine (8), two sterically
congested indole diterpenoids, were accomplished. AlI3-promoted alkyne Prins cyclization …

Bicyclic carbocycles containing a high fraction of Csp3 have become highly attractive
synthetic targets because of the multiple applications they have found in medicinal …

The direct catalytic alkynylation/dehydrative cyclization of 2-amino-3-trifluoroacetyl-pyridines
on water was developed for the efficient synthesis of a broad range of fluorinated 1, 8 …

An economical and efficient protocol for the direct construction of amino skipped diynes
through the Cu (I)-catalyzed reaction of enaminones and terminal alkynes has been …

Alkynes are key motifs in chemistry, serving as precursors in many organic reactions toward
the synthesis of bioactive compounds, polymers, and new materials. Methods to synthesize …

A copper free [Pd]-catalyzed domino intramolecular Heck and intermolecular
decarboxylative Sonogashira couplings, for the synthesis of alkyne bearing heterocyclic …

Described herein is an enantioselective synthesis of an analogue of a previously reported
guaiane endoperoxide isolated from aerial parts of Croton arboreous. The polycyclic …