Influence of maternal thyroid hormones during gestation on fetal brain development

NK Moog, S Entringer, C Heim, PD Wadhwa… - Neuroscience, 2017 - Elsevier
Thyroid hormones (THs) play an obligatory role in many fundamental processes underlying
brain development and maturation. The developing embryo/fetus is dependent on maternal …

Effect of thyroid hormones on neurons and neurodevelopment

G Prezioso, C Giannini, F Chiarelli - Hormone research in paediatrics, 2018 - karger.com
This review focuses on the current knowledge of the effects of thyroid hormones on central
nervous system differentiation and development in animals and the human fetal brain. The …

[HTML][HTML] Expanding the genetic toolkit in Xenopus: Approaches and opportunities for human disease modeling

P Tandon, F Conlon, JD Furlow, ME Horb - Developmental biology, 2017 - Elsevier
The amphibian model Xenopus, has been used extensively over the past century to study
multiple aspects of cell and developmental biology. Xenopus offers advantages of a non …

Comparative assessment of individual and mixture chronic toxicity of glyphosate and glufosinate ammonium on amphibian tadpoles: A multibiomarker approach

APC Boccioni, G Lener, J Peluso, PM Peltzer… - Chemosphere, 2022 - Elsevier
The aim of the present study was to assess the ecotoxicity of glyphosate and glufosinate
ammonium mixtures on amphibian tadpoles and the potential impact of mixture in aquatic …

[HTML][HTML] Tree shrew (Tupaia belangeri) as a novel laboratory disease animal model

J Xiao, R Liu, CS Chen - Zoological research, 2017 - ncbi.nlm.nih.gov
The tree shrew (Tupaia belangeri) is a promising laboratory animal that possesses a closer
genetic relationship to primates than to rodents. In addition, advantages such as small size …

Stress hypothesis overload: 131 hypotheses exploring the role of stress in tradeoffs, transitions, and health

BN Harris - General and Comparative Endocrinology, 2020 - Elsevier
Stress is ubiquitous and thus, not surprisingly, many hypotheses and models have been
created to better study the role stress plays in life. Stress spans fields and is found in the …

Neurodevelopmental impact of the offspring by thyroid hormone system-disrupting environmental chemicals during pregnancy

P Salazar, P Villaseca, P Cisternas… - Environmental Research, 2021 - Elsevier
Everyday use chemicals have been demonstrated to be endocrine disruptors. Since normal
thyroid function during pregnancy is transcendental for the neurodevelopment of the …

Contaminant and environmental influences on thyroid hormone action in amphibian metamorphosis

AA Thambirajah, EM Koide, JJ Imbery… - Frontiers in …, 2019 - frontiersin.org
Aquatic and terrestrial environments are increasingly contaminated by anthropogenic
sources that include pharmaceuticals, personal care products, and industrial and …

Xenopus leads the way: Frogs as a pioneering model to understand the human brain

CRT Exner, HR Willsey - genesis, 2021 - Wiley Online Library
From its long history in the field of embryology to its recent advances in genetics, Xenopus
has been an indispensable model for understanding the human brain. Foundational studies …

The African clawed frog Xenopus laevis: a model organism to study regeneration of the central nervous system

D Lee-Liu, EE Méndez-Olivos, R Muñoz, J Larraín - Neuroscience letters, 2017 - Elsevier
While an injury to the central nervous system (CNS) in humans and mammals is irreversible,
amphibians and teleost fish have the capacity to fully regenerate after severe injury to the …