Transdermal permeation of drugs in various animal species

H Todo - Pharmaceutics, 2017 - mdpi.com
Excised human skin is utilized for in vitro permeation experiments to evaluate the safety and
effect of topically-applied drugs by measuring its skin permeation and concentration …

Halal cosmetics: A review on ingredients, production, and testing methods

K Sugibayashi, E Yusuf, H Todo, S Dahlizar, P Sakdiset… - Cosmetics, 2019 - mdpi.com
The demand for halal cosmetic products among the 2.4 billion Muslim consumers worldwide
is increasing. However, the demand for halal cosmetics remains unmet because cosmetics …

Prediction of skin permeation by chemical compounds using the artificial membrane, Strat-M™

T Uchida, WR Kadhum, S Kanai, H Todo… - European Journal of …, 2015 - Elsevier
Purpose The usefulness of the synthetic membrane, Strat-M™ as an alternative to human
and animal skins was evaluated by estimating the skin permeabilities of chemical …

Finite and infinite dosing: Difficulties in measurements, evaluations and predictions

D Selzer, MMA Abdel-Mottaleb, T Hahn… - Advanced drug delivery …, 2013 - Elsevier
Due to the increased demand for reliable data regarding penetration into and permeation
across human skin, assessment of the absorption of xenobiotics has been gaining in …

Improving the membrane permeability of 5-fluorouracil via cocrystallization

XL Dai, S Li, JM Chen, TB Lu - Crystal Growth & Design, 2016 - ACS Publications
Pharmaceutical cocrystallization is proposed as a new method to enhance membrane
permeability of a BCS class III model drug, 5-fluorouracil (5FU). Three cocrystals of 5FU …

Digital twins for tissue culture techniques—concepts, expectations, and state of the art

J Möller, R Pörtner - Processes, 2021 - mdpi.com
Techniques to provide in vitro tissue culture have undergone significant changes during the
last decades, and current applications involve interactions of cells and organoids, three …

Three-dimensional skin models as tools for transdermal drug delivery: challenges and limitations

M Van Gele, B Geusens, L Brochez… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Transdermal drug delivery has several known advantages over the oral route
and hypodermic injections. The number of drugs that can be taken up transdermally is …

Soft magnetic microrobot doped with porous silica for stability-enhanced multimodal locomotion in a nonideal environment

S Li, D Liu, Y Hu, Z Su, X Zhang, R Guo… - ACS Applied Materials …, 2022 - ACS Publications
As an emerging field of robotics, magnetic-field-controlled soft microrobot has broad
application prospects for its flexibility, locomotion diversity, and remote controllability …

Alternative therapy of rheumatoid arthritis with a novel transdermal patch containing Siegesbeckiae Herba extract

P Quan, B Jiao, R Shang, C Liu, L Fang - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Siegesbeckiae Herba (SiH) is a traditional anti-
rheumatic herbal medicine in China. A SiH derived product, Phynova Joint and Muscle …

Usefulness of Artificial Membrane, Strat-M®, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions

FJ Arce, N Asano, GL See, S Itakura, H Todo… - Pharmaceutics, 2020 - mdpi.com
The ban on the use of animals in testing cosmetic products has led to the development of
animal-free in vitro methods. Strat-M® is an artificial membrane engineered to mimic human …