Carbon− heteroatom bond formations are very important reactions in organic synthesis and
have attracted the interest of many synthetic organic chemists, leading them to develop new …

The Michael addition reaction represents one of the most powerful methods for the formation
of carbon–carbon bonds in organic synthesis. Thanks to the rapid development of …

A copper-catalyzed diastereo-and enantioselective decarboxylative [3+ 2] cyclization
reaction of alkyne-substituted cyclic carbamates with azlactones has been established. A …

Azlactones (also known as oxazolones) are heterocycles usually employed in the
stereoselective synthesis of α, α‐amino acids, heterocycles and natural products. The …

Phosphine-catalyzed regiodivergent enantioselective C-2-and C-4-selective γ-additions of
oxazolones to 2, 3-butadienoates have been developed. The C-4-selective γ-addition of …

A chiral phosphoric acid-catalyzed approach constructing dihydrocoumarin motifs by the
addition of azlactones to para-quinone methides (p-QMs) was developed. The reaction …

We report a highly diastereo-and enantioselective allylation of azlactones catalyzed by the
combination of a metallacyclic iridium complex and an optically inactive phosphate anion …

Catalytic and asymmetric Michael reactions constitute very powerful tools for the
construction of new C–C bonds in synthesis, but most of the reports claiming high selectivity …

This work describes the first enantioselective 1, 6-additions of azlactones to para-quinone
methides. In the presence of a chiral phosphoric acid, 1, 6-adducts were obtained in high …

A vinylog of Michael addition (1, 6-addition) of azlactones to δ-substituted dienyl N-
acylpyrroles has been developed with virtually complete 1, 6-, diastereo-, and …