Radiotherapy of high-grade gliomas: dealing with a stalemate

G Frosina - Critical Reviews in Oncology/Hematology, 2023 - Elsevier
This article discusses the studies on radiotherapy of high-grade gliomas published between
January 1, 2022, and June 30, 2022, with special reference to their molecular biology basis …

[HTML][HTML] Emerging and Biological Concepts in Pediatric High-Grade Gliomas

A Yoel, S Adjumain, Y Liang, P Daniel, R Firestein… - Cells, 2024 - mdpi.com
Primary central nervous system tumors are the most frequent solid tumors in children,
accounting for over 40% of all childhood brain tumor deaths, specifically high-grade …

Intelligence and executive function are associated with age at insult, time post-insult, and disability following chronic pediatric acquired brain injury

AE Brandt, TB Rø, TG Finnanger, RE Hypher… - Frontiers in …, 2024 - frontiersin.org
Background Pediatric acquired brain injury (pABI) profoundly affects cognitive functions,
encompassing IQ and executive functions (EFs). Particularly, young age at insult may lead to …

Comparison of neurocognitive functioning and fine motor skills in pediatric cancer survivors and healthy children

N Chipeeva, A Deviaterikova, E Glebova, E Romanova… - Cancers, 2022 - mdpi.com
Simple Summary Various impairments in neurocognitive and fine motor skills represent a
common side effect of both pediatric tumors and their therapy in children. Here we compare …

Exploring chronomodulated radiotherapy strategies in a chaotic population model

GM Ramírez-Ávila, J Kurths, D Gonze… - Chaos, Solitons & Fractals, 2023 - Elsevier
We present a simple nonlinear model describing the population dynamics of cancerous,
healthy, and effector cells submitted to ionizing radiation. We examine the situations in …

OV Modulators of the Paediatric Brain TIME: Current Status, Combination Strategies, Limitations and Future Directions

K Vazaios, RE van Berkum, FG Calkoen… - International Journal of …, 2024 - mdpi.com
Oncolytic viruses (OVs) are characterised by their preference for infecting and replicating in
tumour cells either naturally or after genetic modification, resulting in oncolysis. Furthermore …

The development of fatigue after treatment for pediatric brain tumors does not differ between tumor locations

E Irestorm, AYN Schouten‐van Meeteren… - Pediatric Blood & …, 2024 - Wiley Online Library
Background Children and adolescents treated for a brain tumor suffer from more fatigue than
survivors of other types of childhood cancer. As tumor location might be predictive of fatigue …

[HTML][HTML] Overcoming the limits of pediatric brain tumor radiotherapy: The use of preclinical 3D models

E Czuba, M Deschuyter, N Entz-Werlé, G Noël… - Cancer …, 2024 - Elsevier
Radiotherapy (RT) is an integral part of managing pediatric brain tumors, yet many patients
develop tumor radioresistance, leading to recurrence and poor clinical outcomes. In …

Improving brain tumor treatment with better imaging and real-time therapy using quantum dots

A Karthik, SS Aalam, M Sivakumar… - … Signal Processing and …, 2024 - Elsevier
Recent advancements in medical imaging and therapeutic technologies have propelled
innovative strategies in brain tumor treatment. This study introduces a comprehensive …

Limited Research Investigating the Value of MRI in Predicting Future Cognitive Morbidity in Survivors of Paediatric Brain Tumours: A Call to Action for Clinical …

D Griffiths-King, C Delivett, A Peet, J Waite, J Novak - medRxiv, 2024 - medrxiv.org
Survivors of pediatric brain tumour patients are at high risk of cognitive morbidity. There is
clinical benefit in being able to reliably predict, at the individual patient level, whether a …