Paramagnetic chemical probes for studying biological macromolecules
Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR)
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
Pseudocontact shifts in biomolecular NMR spectroscopy
T Müntener, D Joss, D Häussinger… - Chemical Reviews, 2022 - ACS Publications
Paramagnetic centers in biomolecules, such as specific metal ions that are bound to a
protein, affect the nuclei in their surrounding in various ways. One of these effects is the …
protein, affect the nuclei in their surrounding in various ways. One of these effects is the …
[PDF][PDF] Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags
Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags Page 1 1
Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags Christoph …
Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags Christoph …
Gd 3+ spin labeling for distance measurements by pulse EPR spectroscopy
D Goldfarb - Physical Chemistry Chemical Physics, 2014 - pubs.rsc.org
Methods for measuring nanometer scale distances between specific sites in biomolecules
(proteins and nucleic acids) and their complexes are essential for describing and analyzing …
(proteins and nucleic acids) and their complexes are essential for describing and analyzing …
Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution
KD Brewer, T Bacaj, A Cavalli, C Camilloni… - Nature structural & …, 2015 - nature.com
Rapid neurotransmitter release depends on the Ca2+ sensor Synaptotagmin-1 (Syt1) and
the SNARE complex formed by synaptobrevin, syntaxin-1 and SNAP-25. How Syt1 triggers …
the SNARE complex formed by synaptobrevin, syntaxin-1 and SNAP-25. How Syt1 triggers …
[HTML][HTML] Covalency and magnetic anisotropy in lanthanide single molecule magnets: the DyDOTA archetype
Lanthanide ions when complexed by polyamino-polycarboxylate chelators form a class of
compounds of paramount importance in several research and technological areas …
compounds of paramount importance in several research and technological areas …
NMR methods to characterize protein-ligand interactions
S Maity, RK Gundampati… - Natural Product …, 2019 - journals.sagepub.com
Structural information pertaining to the interactions between biological macromolecules and
ligands is of potential significance for understanding of molecular mechanisms in key …
ligands is of potential significance for understanding of molecular mechanisms in key …
Design and applications of lanthanide chelating tags for pseudocontact shift NMR spectroscopy with biomacromolecules
D Joss, D Häussinger - Progress in nuclear magnetic resonance …, 2019 - Elsevier
In this review, lanthanide chelating tags and their applications to pseudocontact shift NMR
spectroscopy as well as analysis of residual dipolar couplings are covered. A complete …
spectroscopy as well as analysis of residual dipolar couplings are covered. A complete …
Binding of low molecular weight inhibitors promotes large conformational changes in the dengue virus NS2B-NS3 protease: fold analysis by pseudocontact shifts
L de la Cruz, THD Nguyen, K Ozawa… - Journal of the …, 2011 - ACS Publications
The two-component dengue virus NS2B-NS3 protease (DEN NS2B-NS3pro) is an
established drug target, but inhibitor design is hampered by the lack of a crystal structure of …
established drug target, but inhibitor design is hampered by the lack of a crystal structure of …
Protein structure determination from pseudocontact shifts using ROSETTA
Paramagnetic metal ions generate pseudocontact shifts (PCSs) in nuclear magnetic
resonance spectra that are manifested as easily measurable changes in chemical shifts …
resonance spectra that are manifested as easily measurable changes in chemical shifts …