Salivary gland carcinoma: novel targets to overcome treatment resistance in advanced disease

L Di Villeneuve, IL Souza, FDS Tolentino… - Frontiers in …, 2020 - frontiersin.org
Salivary gland carcinomas (SGC) account for less than 5% of head and neck malignant
neoplasms, further subcategorized in over 20 histological subtypes. For the most part …

Mucoepidermoid carcinoma. An update and review of the literature

A Peraza, R Gómez, J Beltran, FJ Amarista - Journal of stomatology, oral …, 2020 - Elsevier
Abstract Objective Mucoepidermoid Carcinoma (MEC) is the most common malignant
salivary gland neoplasm, representing 10 to 15% of all salivary neoplasms. A review of the …

Management of salivary gland malignancy: ASCO guideline

JL Geiger, N Ismaila, B Beadle, JJ Caudell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To provide evidence-based recommendations for practicing physicians and
other healthcare providers on the management of salivary gland malignancy. METHODS …

Early HPV ctDNA kinetics and imaging biomarkers predict therapeutic response in p16+ oropharyngeal squamous cell carcinoma

Y Cao, CT Haring, C Brummel, C Bhambhani… - Clinical Cancer …, 2022 - AACR
Purpose: In locally advanced p16+ oropharyngeal squamous cell carcinoma (OPSCC),(i) to
investigate kinetics of human papillomavirus (HPV) circulating tumor DNA (ctDNA) and …

Molecular pathology of salivary gland neoplasms: diagnostic, prognostic, and predictive perspective

MH Toper, S Sarioglu - Advances in anatomic pathology, 2021 - journals.lww.com
Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In
recent years, there has been considerable progress in efforts to reveal the molecular …

Mucoepidermoid Carcinoma: A Comparison of Histologic Grading Systems and Relationship to: MAML2: Rearrangement and Prognosis

NA Cipriani, JJ Lusardi, J McElherne… - The American journal …, 2019 - journals.lww.com
Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy, but
categorization is complicated by variability in grading systems and uncertain prognostic …

MAML2 rearrangements in variant forms of mucoepidermoid carcinoma: ancillary diagnostic testing for the ciliated and warthin-like variants

JA Bishop, ML Cowan, CH Shum… - The American journal of …, 2018 - journals.lww.com
Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. Recent
studies have shown that most MECs harbor gene fusions involving MAML2—an alteration …

[HTML][HTML] The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma

Z Chen, W Ni, JL Li, S Lin, X Zhou, Y Sun, JW Li… - JCI insight, 2021 - ncbi.nlm.nih.gov
No effective systemic treatment is available for patients with unresectable, recurrent, or
metastatic mucoepidermoid carcinoma (MEC), the most common salivary gland malignancy …

Current state of knowledge on salivary gland cancers

HH Lin, KH Limesand, DK Ann - Critical Reviews™ in …, 2018 - dl.begellhouse.com
Salivary gland cancers (SGCs), categorized as head and neck cancers (HNCs), constitute
about 6% of head and neck cancer diagnoses based on estimate by American Head and …

Molecular targets in salivary gland cancers: a comprehensive genomic analysis of 118 mucoepidermoid carcinoma tumors

M Bou Zerdan, PA Kumar, D Zaccarini, J Ross… - Biomedicines, 2023 - mdpi.com
Introduction: Salivary gland carcinomas (SGC) are histologically diverse cancers and next-
generation sequencing (NGS) to identify key molecular targets is an important aspect in the …