Treatments for Alzheimer's disease (AD) directed against the prominent amyloid plaque
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …

Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …

Ischemic stroke represents a significant danger to human beings, especially the elderly.
Interventions are only available to remove the clot, and the mechanism of neuronal death …

Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …

The spreading of misfolded alpha-synuclein (α-syn) protein has been observed in animal
models of Parkinson's disease (PD) and other α-synucleinopathies that mimic human PD …

Alzheimer's disease (AD) is the most prevalent cause of dementia, accounting for
approximately 60%–80% of all cases. Although much effort has been made over the years …

Essential trace metals like zinc (Zn), iron (Fe), and copper (Cu) play an important
physiological role in the metabolomics and healthy functioning of body organs, including the …

Hemoglobin and iron overload is considered the major contributor to intracerebral
hemorrhage (ICH)-induced brain injury. Accumulation of iron in the brain leads to microglia …

Deep tissue injuries (DTIs) are a serious type of pressure injuries that mainly occur at the
bony prominences and can develop rapidly, making prevention and treatment more difficult …