Hormonal regulation of mammary gland development and lactation

FM Hannan, T Elajnaf, LN Vandenberg… - Nature Reviews …, 2023 - nature.com
Lactation is critical to infant short-term and long-term health and protects mothers from
breast cancer, ovarian cancer and type 2 diabetes mellitus. The mammary gland is a …

“Do we know jack” about JAK? A closer look at JAK/STAT signaling pathway

E Bousoik, H Montazeri Aliabadi - Frontiers in oncology, 2018 - frontiersin.org
Janus tyrosine kinase (JAK) family of proteins have been identified as crucial proteins in
signal transduction initiated by a wide range of membrane receptors. Among the proteins in …

[HTML][HTML] Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype

K Gabrusiewicz, B Rodriguez, J Wei, Y Hashimoto… - JCI insight, 2016 - ncbi.nlm.nih.gov
Glioblastomas are highly infiltrated by diverse immune cells, including microglia,
macrophages, and myeloid-derived suppressor cells (MDSCs). Understanding the …

Prolactin: A hormone with diverse functions from mammary gland development to cancer metastasis

ÖK Atıcı, N Govindrajan, I Lopetegui-González… - Seminars in Cell & …, 2021 - Elsevier
Prolactin has a rich mechanistic set of actions and signaling in order to elicit developmental
effects in mammals. Historically, prolactin has been appreciated as an endocrine peptide …

Genome-wide association study reveals candidate genes for litter size traits in pelibuey sheep

W Hernández-Montiel, MA Martínez-Núñez… - Animals, 2020 - mdpi.com
Simple Summary Reproductive traits are economically important in the livestock industry,
and this is of greater relevance when it comes to indigenous animals, since their study …

Double-edged sword of JAK/STAT signaling pathway in viral infections: novel insights into virotherapy

M Mahjoor, G Mahmoudvand, S Farokhi… - Cell Communication and …, 2023 - Springer
The Janus kinase/signal transducer and activator of transcription (JAK/STAT) is an intricate
signaling cascade composed of various cytokines, interferons (IFN, growth factors, and other …

Secretion and function of pituitary prolactin in evolutionary perspective

A Dobolyi, S Oláh, D Keller, R Kumari… - Frontiers in …, 2020 - frontiersin.org
The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient
vertebrate hormone released from the pituitary that exerts particularly diverse functions. The …

Prolactin actions

ND Horseman, KA Gregerson - Journal of Molecular …, 2014 - jme.bioscientifica.com
Molecular genetics and other contemporary approaches have contributed to a better
understanding of prolactin (PRL) actions at the cellular and organismal levels. In this review …

A network map of BDNF/TRKB and BDNF/p75NTR signaling system

VK Sandhya, R Raju, R Verma, J Advani… - Journal of cell …, 2013 - Springer
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[HTML][HTML] Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes

NN Singh, S Hoffman, PP Reddi, RN Singh - Biochimica et Biophysica Acta …, 2021 - Elsevier
Spinal muscular atrophy (SMA) is one of the major genetic disorders associated with infant
mortality. More than 90% of cases of SMA result from deletions of or mutations in the …