Naringenin: A potential flavonoid phytochemical for cancer therapy

M Motallebi, M Bhia, HF Rajani, I Bhia, H Tabarraei… - Life Sciences, 2022 - Elsevier
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …

Molecular mechanisms of the anti-obesity and anti-diabetic properties of flavonoids

M Kawser Hossain, A Abdal Dayem, J Han… - International journal of …, 2016 - mdpi.com
Obesity and diabetes are the most prevailing health concerns worldwide and their incidence
is increasing at a high rate, resulting in enormous social costs. Obesity is a complex disease …

[HTML][HTML] Cytotoxicity of dietary flavonoids on different human cancer types

K Sak - Pharmacognosy reviews, 2014 - ncbi.nlm.nih.gov
Flavonoids are ubiquitous in nature. They are also in food, providing an essential link
between diet and prevention of chronic diseases including cancer. Anticancer effects of …

Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent

A Rauf, MA Shariati, M Imran, K Bashir… - … Science and Pollution …, 2022 - Springer
Though the incidence of several cancers in Western societies is regulated wisely, some
cancers such as breast, lung, and colorectal cancer are currently rising in many low-and …

Dietary flavonoids and acarbose synergistically inhibit α-glucosidase and lower postprandial blood glucose

B Zhang, X Li, W Sun, Y Xing, Z Xiu… - Journal of agricultural …, 2017 - ACS Publications
The inhibition of porcine pancreatic α-amylase and mammalian α-glucosidase by 16
individual flavonoids was determined. The IC50 values for baicalein,(+)-catechin, quercetin …

The anti-cancer effect of polyphenols against breast cancer and cancer stem cells: molecular mechanisms

A Abdal Dayem, HY Choi, GM Yang, K Kim, SK Saha… - Nutrients, 2016 - mdpi.com
The high incidence of breast cancer in developed and developing countries, and its
correlation to cancer-related deaths, has prompted concerned scientists to discover novel …

Naringenin (citrus flavonone) induces growth inhibition, cell cycle arrest and apoptosis in human hepatocellular carcinoma cells

D Arul, P Subramanian - Pathology & Oncology Research, 2013 - Springer
Search for new substances with antiproliferative activity and apoptosis inducing potential
towards HepG2 cells is important since HCC is notoriously resistant to conventional …

Hyaluronic acid decorated naringenin nanoparticles: Appraisal of chemopreventive and curative potential for lung cancer

P Parashar, M Rathor, M Dwivedi, SA Saraf - Pharmaceutics, 2018 - mdpi.com
Lung carcinoma is the most common cancer in men and second in women (preceded by
breast cancer) worldwide. Around 1 in 10 of all cancers diagnosed in men, lung cancer …

Naringenin attenuates mucous hypersecretion by modulating reactive oxygen species production and inhibiting NF-κB activity via EGFR-PI3K-Akt/ERK MAPKinase …

J Yang, Q Li, XD Zhou, VP Kolosov… - Molecular and cellular …, 2011 - Springer
Naringenin (Nar) is a flavonoid derived from plant foods. It has been shown to have anti-
inflammatory properties. Many studies have shown that overexpression of reactive oxygen …

Cytotoxicity of naringenin induces Bax‐mediated mitochondrial apoptosis in human lung adenocarcinoma A549 cells

WL Lu, CTR Yu, HM Lien, GT Sheu… - Environmental …, 2020 - Wiley Online Library
Naringenin (NGEN), a natural flavonoid has growth inhibition and apoptosis‐inducing
activities in several cancer cells. However, the cytotoxicity mechanisms of NGEN in cell …