Infectious origin of Alzheimer's disease: Amyloid beta as a component of brain antimicrobial immunity

I Vojtechova, T Machacek, Z Kristofikova… - PLoS …, 2022 - journals.plos.org
The amyloid cascade hypothesis, focusing on pathological proteins aggregation, has so far
failed to uncover the root cause of Alzheimer's disease (AD), or to provide an effective …

Knowledge gaps in the epidemiology of Toxocara: the enigma remains

CV Holland - Parasitology, 2017 - cambridge.org
Toxocara species infect a wide range of companion, domestic and wild animals as definitive
and paratenic hosts, via multiple routes of transmission, producing long-lived tissue …

Global toxocariasis research trends from 1932 to 2015: a bibliometric analysis

SH Zyoud - Health Research Policy and Systems, 2017 - Springer
Background Toxocariasis is a highly prevalent parasitic disease in the tropical regions of the
world, with its impact on public health being typically underestimated. To better recognise …

Global profiling of lncRNAs-miRNAs-mRNAs reveals differential expression of coding genes and non-coding RNAs in the lung of beagle dogs at different stages of …

WB Zheng, Y Zou, JJ He, HM Elsheikha, GH Liu… - International Journal for …, 2021 - Elsevier
The roundworm Toxocara canis causes toxocariasis in dogs and larval migrans in humans.
Better understanding of the lung response to T. canis infection could explain why T. canis …

Neuroinvasion of Toxocara canis- and T. cati-larvae mediates dynamic changes in brain cytokine and chemokine profile

P Waindok, C Strube - Journal of neuroinflammation, 2019 - Springer
Background Neurotoxocarosis (NT) is induced by larvae of the dog or cat roundworm
(Toxocara canis or T. cati) migrating and persisting in the central nervous system of …

Histopathological characterization of Toxocara canis- and T. cati-induced neurotoxocarosis in the mouse model

A Springer, L Heuer, E Janecek-Erfurth, A Beineke… - Parasitology …, 2019 - Springer
Infective larvae of Toxocara canis and T. cati, the common roundworms of dogs and cats,
may invade the central nervous system of paratenic hosts, including humans, causing …

Toxocara “omics” and the promises it holds for medicine and veterinary medicine

WB Zheng, Y Zou, XQ Zhu, GH Liu - Advances in Parasitology, 2020 - Elsevier
Toxocariasis is one of the most neglected worldwide zoonoses that is caused by larval
nematode parasites of the genus Toxocara, Toxocara canis, and to a lesser extent, Toxocara …

Abnormal neurobehaviour and impaired memory function as a consequence of Toxocara canis- as well as Toxocara cati-induced neurotoxocarosis

E Janecek, P Waindok, M Bankstahl… - PLoS neglected tropical …, 2017 - journals.plos.org
Background Neuroinvasive larvae of the worldwide occurring zoonotic roundworms
Toxocara canis and T. cati may induce neurotoxocarosis (NT) in humans, provoking a …

Toxocara canis- and Toxocara cati-Induced Neurotoxocarosis Is Associated with Comprehensive Brain Transcriptomic Alterations

P Waindok, E Janecek-Erfurth, DL Lindenwald, E Wilk… - Microorganisms, 2022 - mdpi.com
Toxocara canis and Toxocara cati are globally occurring zoonotic roundworms of dogs and
cats. Migration and persistence of Toxocara larvae in the central nervous system of …

Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the …

G Ma, T Wang, PK Korhonen, S Nie, GE Reid… - Parasites & vectors, 2019 - Springer
Background Toxocara canis is quite closely related to Ascaris suum but its biology is more
complex, involving a phase of arrested development (diapause or hypobiosis) in tissues as …