Coronary microvascular dysfunction (CMD) encompasses several pathogenetic
mechanisms involving coronary microcirculation and plays a major role in determining …

Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Sharmila Dorbala, MD, MPH, FASNC, Chair*; Yukio Ando, MD, PhD†; Sabahat Bokhari,
MD‡; Angela Dispenzieri, MD § ; Rodney H. Falk, MD*; Victor A. Ferrari, MD∥; Marianna …

Coronary microvascular disease (CMD) refers to the subset of disorders affecting the
structure and function of the coronary microcirculation, is prevalent in patients across a …

Since the 2007 publication of the American Society of Echocardiography (ASE) guidelines
for stress echocardiography, 1 new information has become available about the …

The amyloidoses are a group of protein-folding disorders in which≥ 1 organ is infiltrated by
proteinaceous deposits known as amyloid. The deposits are derived from 1 of several …

Cardiac amyloidosis (CA) is one of the most rapidly progressive forms of heart disease, with
a median survival from diagnosis, if untreated, ranging from< 6 months for light chain …

Radionuclide myocardial perfusion imaging (MPI) is among the most commonly performed
diagnostic tests in cardiology. Although the diagnostic and prognostic applications of …

The amyloidoses are a group of systemic diseases characterized by organ deposition of
misfolded protein fragments of diverse origins. The natural history of the disease …

The endothelium, by area alone, is one of the largest organs in the body comprised of up to
trillion cells, weighing over 1 kg, and covering nearly 3 m2 in a 70 kg male. 1, 2 Moreover, it …