The genus Pseudomonas described in 1894 is one of the most diverse and ubiquitous
bacterial genera which encompass species isolated worldwide. In the last years more than …

The carbapenems remain some of the most effective options available for treating patients
with serious infections due to Gram-negative bacteria. Carbapenemases are enzymes that …

Antimicrobial therapy promotes resistance emergence in target infections and in off-target
microbiota. Off-target resistance emergence threatens patient health when off-target …

Abstract Background Carbapenem-resistant Pseudomonas aeruginosa (CRPA) colonizes
the gastrointestinal tract of intensive care unit (ICU) patients, and CRPA colonization puts …

Health care-associated infections such as Pseudomonas aeruginosa bacteremia pose a
major clinical risk for hospitalized patients. However, these systemic infections are …

Pseudomonas aeruginosa may become multidrug-resistant (MDR) due to multiple inherited
and acquired resistance mechanisms. The human gastrointestinal tract is known as a …

Intestinal barrier derangement allows intestinal bacteria and their products to translocate to
the systemic circulation. Pseudomonas aeruginosa (PA) superimposed infection in critically …

In the last decades, we have witnessed a steady increase in infections caused by multidrug-
resistant (MDR) bacteria. These infections are associated with higher morbidity and …

Pseudomonas aeruginosa (P. aeruginosa) remains a prominent nosocomial pathogen
responsible for high morbi-mortality in intensive care units (ICUs). P. aeruginosa …

Background Transmission of antimicrobial-resistant Gram-negative bacteria (AMR-GNB)
amongst hospitalised patients can lead to new cases of carriage, infection and outbreaks …