Electrophilicity, mechanism and structure–reactivity relationships of cyclic secondary amines addition to 2-methoxy-3, 5-dinitropyridine

T Slama, O Amamou, A Hedhli, JC Guillemin… - Journal of Molecular …, 2024 - Elsevier
The second-order rate constants (k) for the nucleophilic aromatic substitution reactions of 2‑
methoxy-3, 5-dinitropyridine 1 with secondary cyclic amines 2a-c in acetonitrile solution at …

4a Nucleophilic Aromatic Substitution

MR Crampton - Organic Reaction Mechanisms 2020, 2024 - Wiley Online Library
Analogies between the mechanisms of electrophilic substitution and nucleophilic
substitution have been discussed. Theoretical calculations, involving aromaticity …

Nonlinear Brønsted and Hammett Correlations Associated with Reactions of 4‐Chloro‐7‐nitrobenzofurazan with Anilines in Dimethyl Sulfoxide Solution

I Jmaoui, T Boubaker… - International Journal of …, 2013 - Wiley Online Library
The kinetics and mechanism of nucleophilic aromatic substitution reactions of 4‐chloro‐7‐
nitrobenzofurazan 1 with 4‐X‐substituted anilines 2a–g (X= OH, OCH3, CH3, H, I, Cl, and …

Solvent effect, quantification and correlation analysis of the nucleophilicities of cyclic secondary amines

R Hanen, M Faouzi, A Sahbi, B Taoufik - Chemical Papers, 2023 - Springer
Kinetics of the SNAr reactions of four 7-L-4-nitrobenzofurazans 1a-d (L= Cl, OC6H5, OCH3,
Im+, Cl−) with three cyclic secondary amines 2a-c in methanol as well as in …

A theoretical and electrochemical impedance spectroscopy study of the adsorption and sensing of selected metal ions by 4-morpholino-7-nitrobenzofuran

I Chérif, B Gassoumi, H Ayachi, M Echabaane… - Heliyon, 2024 - cell.com
The selectivity of a novel chemosensor, based on a modified nitrobenzofurazan referred to
as NBD-Morph, has been investigated for the detection of heavy metal cations (Co 2+, Pb …

Nucleophilicity Parameters for Nitroalkyl Anions in Methanol and Structure‐Reactivity Analysis

F Necibi, S Ben Salah, JC Hierso… - …, 2023 - Wiley Online Library
A kinetic study is reported for the addition of nitroalkyl anions 2 a–c at the C‐7 position of the
4‐nitrobenzochalcogenadiazoles 1 a–c in methanol at 20° C. By using the Mayr approach …

Substituent effects on the reactions of aromatic triflones with para‐X‐anilines in methanol: Low intrinsic reactivity and transition state imbalances

N El Guesmi, T Boubaker - International Journal of Chemical …, 2011 - Wiley Online Library
A kinetic study is reported for SNAr reactions of 2, 4, 6‐tris (trifluoromethanesulfonyl) anisole
1a with a series of para‐X‐substituted anilines 2a–e in a methanol solution at various …

In-depth quantitative and theoretical study of ambident electrophilies of 2-bromo-3-X-5-nitrothiophenes

A Ghabi, R Hamdi, R Khaldi, S Ayachi… - Journal of Molecular …, 2025 - Elsevier
As part of our continuing studies into the electron deficient nature of five-membered ring
heterocycles, specifically 2‑methoxy-3-X-5-nitrothiophenes and 3-X-5-nitrothiophene, we …

Reactivity of diethyl benzylidenemalonates with secondary cyclic amine dimers in acetonitrile: Structure-reactivity relationships and mechanism

A Hedhli, T Slama, O Amamou, S Ayachi… - Journal of Molecular …, 2024 - Elsevier
We report on a kinetic study for the nucleophilic addition reactions of diethyl 4-X-substituted
benzylidenemalonates 1a-c (X= N (CH 3) 2, OCH 3 and CH 3) with N-nucleophiles, such as …

Combined kinetic, and theoretical approaches for the study of the SEAr reactions of 2-(2′, 4′, 6′-trinitrophenyl)-4, 6-dinitrobenzotriazole 1-oxide with 5-R …

O Amamou, A Hedhli, T Slama, S Ayachi, T Boubaker - Chemical Papers, 2024 - Springer
We present a kinetic and theoretical study of electrophilic aromatic substitution (SE Ar)
involving 2-(2′, 4′, 6′-trinitrophenyl)-4, 6-dinitrobenzotriazole 1-oxide 1 with a series of 5 …