Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
[HTML][HTML] Hydrogen sulfide signaling in mitochondria and disease
Hydrogen sulfide can signal through 3 distinct mechanisms: 1) reduction and/or direct
binding of metalloprotein heme centers, 2) serving as a potent antioxidant through reactive …
binding of metalloprotein heme centers, 2) serving as a potent antioxidant through reactive …
Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications
C Szabo - American Journal of Physiology-Cell Physiology, 2017 - journals.physiology.org
Nitric oxide (NO) vascular signaling has long been considered an independent, self-
sufficient pathway. However, recent data indicate that the novel gaseous mediator, hydrogen …
sufficient pathway. However, recent data indicate that the novel gaseous mediator, hydrogen …
The role of hydrogen sulfide on cardiovascular homeostasis: an overview with update on immunomodulation
Hydrogen sulfide (H2S), the third endogenous gaseous signaling molecule alongside nitric
oxide (NO) and carbon monoxide, is synthesized by multiple enzymes in cardiovascular …
oxide (NO) and carbon monoxide, is synthesized by multiple enzymes in cardiovascular …
Role of 3-Mercaptopyruvate sulfurtransferase (3-MST) in physiology and disease
SP Rao, P Dobariya, H Bellamkonda, SS More - Antioxidants, 2023 - mdpi.com
3-mercaptopyruvate sulfurtransferase (3-MST) plays the important role of producing
hydrogen sulfide. Conserved from bacteria to Mammalia, this enzyme is localized in …
hydrogen sulfide. Conserved from bacteria to Mammalia, this enzyme is localized in …
Impaired hydrogen sulfide–mediated vasodilation contributes to microvascular endothelial dysfunction in hypertensive adults
Reductions in hydrogen sulfide (H2S) production have been implicated in the pathogenesis
of vascular dysfunction in animal models of hypertension; however, no studies have …
of vascular dysfunction in animal models of hypertension; however, no studies have …
Erucin exhibits vasorelaxing effects and antihypertensive activity by H2S‐releasing properties
A Martelli, E Piragine, V Citi, L Testai… - British Journal of …, 2020 - Wiley Online Library
Background and Purpose Hydrogen sulfide (H2S)‐releasing agents are viewed as potential
antihypertensive drugs. Recently, natural isothiocyanates emerged as original H2S‐donor …
antihypertensive drugs. Recently, natural isothiocyanates emerged as original H2S‐donor …
Cystathionine γ-Lyase–Produced hydrogen sulfide controls endothelial no bioavailability and blood pressure
Hydrogen sulfide (H2S) and NO are important gasotransmitters, but how endogenous H2S
affects the circulatory system has remained incompletely understood. Here, we show that …
affects the circulatory system has remained incompletely understood. Here, we show that …
The mechanism of action and role of hydrogen sulfide in the control of vascular tone
E Dongó, G Beliczai-Marosi, AS Dybvig, L Kiss - Nitric Oxide, 2018 - Elsevier
Our knowledge about hydrogen sulfide (H 2 S) significantly changed over the last two
decades. Today it is considered as not only a toxic gas but also as a gasotransmitter with …
decades. Today it is considered as not only a toxic gas but also as a gasotransmitter with …