The pleiotropic effects of statins in rheumatoid arthritis

E Aminifar, HS Tavakkol Afshari… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives Rheumatoid arthritis (RA) is an inflammatory and autoimmune disease. Studies
over the past two decades suggest that statins have a beneficial impact on the complications …

Advances and challenges in regenerative therapies for abdominal aortic aneurysm

CL Chao, B Applewhite, NK Reddy… - Frontiers in …, 2024 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a significant source of mortality worldwide and carries a
mortality of greater than 80% after rupture. Despite extensive efforts to develop …

A dual-action Rhein-peptide hydrogel synergistically inhibits inflammation and matrix degradation for therapeutic mitigation of abdominal aortic aneurysm

M Wang, Y Li, Y Bai, Z Lin, S Bi, Y Long, Y Cai… - Chemical Engineering …, 2024 - Elsevier
Abdominal aortic aneurysm (AAA), a life-threatening pathological dilation of the abdominal
aorta, is characterized by chronic inflammation and extracellular matrix degradation. While …

[HTML][HTML] Different Proteins as Biomarkers for Sac Shrinkage After Endovascular Aortic Repair of Abdominal Aortic Aneurysms

A Zimmermann, D Reitnauer, Y Yundung… - Journal of …, 2024 - mdpi.com
Background: This study aims to identify circulating biomarkers by using proteomic analysis
associated with sac shrinkage or expansion in patients undergoing endovascular aneurysm …

[HTML][HTML] Causal Relationships between Lipid-Lowering Drug Target and Aortic Disease and Calcific Aortic Valve Stenosis: A Two-Sample Mendelian Randomization

L Yang, M Xu, X Gao, J Liu, D Zhang… - Reviews in …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9), 3-hydroxy-3-
methylglutaryl-coenzyme A reductase (HMGCR), cholesteryl ester transfer protein (CETP) …

Exploration of small molecule compounds targeting abdominal aortic aneurysm based on CMap database and molecular dynamics simulation

F Li, L Zhuo, F Xie, H Luo, Y Li, H Lin, X Li - Vascular, 2024 - journals.sagepub.com
Objective The mitigation of abdominal aortic aneurysm (AAA) growth through
pharmaceutical intervention offers the potential to avert the perils associated with AAA …

[HTML][HTML] Endovascular Aneurysm Repair Versus Open Surgical Repair in Treating Abdominal Aortic Aneurysm

JR Vienneau, CI Burns, A Boghokian, V Soti - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Abdominal aortic aneurysm (AAA) denotes an abdominal aorta dilation exceeding 3 cm,
typically asymptomatic until rupture, posing severe consequences, including fatality …

CXCL5 通过诱导血管钙化参与颈动脉斑块的形成

亓明, 王磊, 张振 - 中国组织工程研究, 2024 - cjter.com
CXCL5 通过诱导血管钙化参与颈动脉斑块的形成 Page 1 186|中国组织工程研究|第28卷|第2期
|2024年1月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …

Statins: Beneficial Effects in Treatment of COVID-19

NA Lashgari, NM Roudsari, H Shamsnia… - Application of Omic …, 2023 - Springer
The recent viral disease COVID-19 has attracted much attention. The disease is caused by
SARS-CoV-19 virus which has different variants and mutations. The mortality rate of SARS …

Aneurisma de Aorta Abdominal-Aspectos epidemiológicos, fisiopatológicos e manejo terapêutico

AC da Silva Ramos, PV Flores… - Brazilian Journal …, 2023 - ojs.brazilianjournals.com.br
O aneurisma de aorta abdominal (AAA) é uma doença multifatorial, que ocorre quando há
dilatação focal da aorta abdominal-mais de 50% do diâmetro normal-e é mais comum em …