Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …

Cancer stem cells (CSCs) are the main culprits involved in therapy resistance and disease
recurrence in colorectal carcinoma (CRC). Results using cell culture, animal models and …

Pancreatic cancer is a highly fatal malignant tumor of the digestive system. It is characterized
by early metastasis and high mortality rates. Solasonine, a steroidal alkaloid, is derived from …

Sumoylation is an essential post-translational modification that has evolved to regulate
intricate networks within emerging complexities of eukaryotic cells. Thousands of target …

The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …

The peptidyl-prolyl cis-trans isomerase Pin1 is a pivotal therapeutic target in cancers, but the
regulation of Pin1 protein stability is largely unknown. High Pin1 expression is associated …

The histone methyltransferase G9a is well-documented for its implication in neoplastic
growth. However, recent investigations have demonstrated a key involvement of this …

Background We previously reported that miR-203 functions as a tumor suppressor in
ovarian cancer cells by directly targeting transcription factor Snai2 and inhibiting epithelial to …

Due to peritoneal metastasis and frequent recurrence, ovarian cancer has the highest
mortality among gynecological cancers. Epithelial to mesenchymal transition (EMT) …

Aims: Early detection of colorectal cancer (CRC) provides substantially better survival rates.
This study aimed to develop a blood-based screening assay named SPOT-MAS ('screen for …