Autoimmune Polyendocrine Syndromes Autoimmune polyendocrine syndromes comprise a
diverse group of clinical entities involving functional impairment of multiple endocrine glands …

Autoimmune thyroid diseases (AITD) are common autoimmune diseases, affecting up to 5%
of the general population. Thyroid-directed autoimmunity is manifested in two classical …

OBJECTIVE: Individuals with schizophrenia and their relatives tend to have either higher or
lower than expected prevalences of autoimmune disorders, especially rheumatoid arthritis …

Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population.
Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of …

Context: Cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) polymorphisms have been
widely examined for their associations with autoimmune thyroid diseases [Graves' disease …

Background Epidemiological studies report increased comorbidity between depression and
autoimmune diseases. The role of shared genetic influences in the observed comorbidity is …

FOXP3 is a key gene in the development of regulatory T cells (Treg). FOXP3 expression
commits naïve T cells to become Treg cells. Indeed, mutations in the FOXP3 gene cause …

Despite recent evidence that low serum 25-hydroxyvitamin D (25 (OH) D) levels and deflects
may influence the emergence of autoimmune thyroid disorders (AITD), the relationship …

Summary Objective Susceptibility to Graves' disease (GD) is to a significant extent
determined by genetic factors of which the best known are those associated with the HLA …

Previously, we and others have demonstrated the association of a C/T single nucleotide
polymorphism (SNP), in the Kozak sequence of CD40, with Graves' disease (GD). Here …