Molecular pathways of cellular senescence and placental aging in late fetal growth restriction and stillbirth

A Kajdy, J Modzelewski, A Cymbaluk-Płoska… - International journal of …, 2021 - mdpi.com
Abnormally accelerated, premature placental senescence plays a crucial role in the genesis
of pregnancy pathologies. Abnormal growth in the third trimester can present as small for …

Flip a coin: cell senescence at the maternal–fetal interface

GS Gong, KP Muyayalo, YJ Zhang, XX Lin… - Biology of …, 2023 - academic.oup.com
During pregnancy, cell senescence at the maternal–fetal interface is required for maternal
well-being, placental development, and fetal growth. However, recent reports have shown …

[HTML][HTML] Genome diversity and instability in human germ cells and preimplantation embryos

V Shukla, MK Høffding, ER Hoffmann - Seminars in Cell & Developmental …, 2021 - Elsevier
Genome diversity is essential for evolution and is of fundamental importance to human
health. Generating genome diversity requires phases of DNA damage and repair that can …

Evidence of Placental Aging in Late SGA, Fetal Growth Restriction and Stillbirth—A Systematic Review

A Kajdy, D Sys, J Modzelewski, J Bogusławska… - Biomedicines, 2023 - mdpi.com
During pregnancy, the placenta undergoes a natural aging process, which is considered
normal. However, it has been hypothesized that an abnormally accelerated and premature …

The role of placental aging in adverse pregnancy outcomes: A mitochondrial perspective

M Pan, J Zhou, J Wang, W Cao, L Li, L Wang - Life Sciences, 2023 - Elsevier
Premature placental aging is associated with placental insufficiency, which reduces the
functional capacity of the placenta, leading to adverse pregnancy outcomes. Placental …

Cord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth

R Alfano, D Zugna, H Barros, M Bustamante, L Chatzi… - BMC medicine, 2023 - Springer
Background Rapid postnatal growth may result from exposure in utero or early life to
adverse conditions and has been associated with diseases later in life and, in particular …

[HTML][HTML] Analyses of selected tumour-associated factors expression in normotensive and preeclamptic placenta

RM Balahmar, B Ranganathan, V Ebegboni… - Pregnancy …, 2022 - Elsevier
Introduction Human placenta is often considered a controlled-tumour because of shared
properties such as invasion and angiogenesis. We assessed the status of a few selected …

[PDF][PDF] Stefa nska, K.; Rabijewski, M.; Torbé, A.; Kwiatkowski, S. Molecular Pathways of Cellular Senescence and Placental Aging in Late Fetal Growth Restriction and …

A Kajdy, J Modzelewski, A Cymbaluk-Płoska… - Int. J. Mol. Sci, 2021 - academia.edu
Abnormally accelerated, premature placental senescence plays a crucial role in the genesis
of pregnancy pathologies. Abnormal growth in the third trimester can present as small for …