Melanoma, melanin, and melanogenesis: The Yin and Yang relationship

RM Slominski, T Sarna, PM Płonka, C Raman… - Frontiers in …, 2022 - frontiersin.org
Melanin pigment plays a critical role in the protection against the harmful effects of ultraviolet
radiation and other environmental stressors. It is produced by the enzymatic transformation …

Current state of melanoma diagnosis and treatment

LE Davis, SC Shalin, AJ Tackett - Cancer biology & therapy, 2019 - Taylor & Francis
Melanoma is the deadliest form of skin cancer. In the early stages, melanoma can be treated
successfully with surgery alone and survival rates are high, but after metastasis survival …

Regulating the absorption spectrum of polydopamine

Y Zou, X Chen, P Yang, G Liang, Y Yang, Z Gu… - Science advances, 2020 - science.org
Polydopamine (PDA) has been increasingly exploited as an advanced functional material,
and its emergent light absorption property plays a crucial role in determining various …

Flexible hybrid electronics for digital healthcare

Y Ma, Y Zhang, S Cai, Z Han, X Liu, F Wang… - Advanced …, 2020 - Wiley Online Library
Recent advances in material innovation and structural design provide routes to flexible
hybrid electronics that can combine the high‐performance electrical properties of …

Endogenous photosensitizers in human skin

EL Bastos, FH Quina, MS Baptista - Chemical Reviews, 2023 - ACS Publications
Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …

Oxidative stress in the skin: Impact and related protection

J Chen, Y Liu, Z Zhao, J Qiu - International Journal of Cosmetic …, 2021 - Wiley Online Library
Skin, our first interface to the external environment, is subjected to oxidative stress caused
by a variety of factors such as solar ultraviolet, infrared and visible light, environmental …

Singlet molecular oxygen reactions with nucleic acids, lipids, and proteins

P Di Mascio, GR Martinez, S Miyamoto… - Chemical …, 2019 - ACS Publications
Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently
reacting with cellular constituents. The resulting oxidatively generated damage to nucleic …

[HTML][HTML] Polyphenol-based hydrogels: Pyramid evolution from crosslinked structures to biomedical applications and the reverse design

Z Li, Z Chen, H Chen, K Chen, W Tao, X Ouyang… - Bioactive Materials, 2022 - Elsevier
As a kind of nature-derived bioactive materials, polyphenol-based hydrogels possess many
unique and outstanding properties such as adhesion, toughness, and self-healing due to …

Photoprotection and skin pigmentation: Melanin-related molecules and some other new agents obtained from natural sources

F Solano - Molecules, 2020 - mdpi.com
Direct sun exposure is one of the most aggressive factors for human skin. Sun radiation
contains a range of the electromagnetic spectrum including UV light. In addition to the …

Formation of UV-induced DNA damage contributing to skin cancer development

J Cadet, T Douki - Photochemical & Photobiological Sciences, 2018 - pubs.rsc.org
UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …