Synthetic cells in biomedical applications

W Sato, T Zajkowski, F Moser… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …

Twenty-five years of polymersomes: lost in translation?

S Matoori, JC Leroux - Materials Horizons, 2020 - pubs.rsc.org
Soon after the discovery of polymeric vesicles (polymersomes), reports of their high
membrane stability raised hopes for the development of next generation vesicles for drug …

Pharmacokinetics of lipid-drug conjugates loaded into liposomes

RD Signorell, P Luciani, D Brambilla… - European Journal of …, 2018 - Elsevier
Drugs that are neither lipophilic nor suitable for encapsulation via remote loading
procedures are generally characterized by low entrapment efficiencies and poor retention in …

Tuning the envelope structure of enzyme nanoreactors for in vivo detoxification of organophosphates

T Pashirova, Z Shaihutdinova, D Tatarinov… - International Journal of …, 2023 - mdpi.com
Encapsulated phosphotriesterase nanoreactors show their efficacy in the prophylaxis and
post-exposure treatment of poisoning by paraoxon. A new enzyme nanoreactor (E-nRs) …

[HTML][HTML] Mechanism of surfactant interactions with feline coronavirus: A physical chemistry perspective

H Mateos, A Mallardi, M Camero, G Lanave… - Journal of Colloid and …, 2024 - Elsevier
Hypothesis Surfactants are inexpensive chemicals with promising applications in virus
inactivation, particularly for enveloped viruses. Yet, the detailed mechanisms by which …

Highly chelating stellate mesoporous silica nanoparticles for specific iron removal from biological media

P Duenas-Ramirez, C Bertagnolli, R Müller… - Journal of Colloid and …, 2020 - Elsevier
In this work, the design of a new generation of functionalized large pore silica nanoparticles
is addressed for the specific removal of iron from biological environments. Herein …

Increasing the removal of protein‐bound uremic toxins by liposome‐supported hemodialysis

Y Shi, Y Wang, S Ma, T Liu, H Tian, Q Zhu… - Artificial …, 2019 - Wiley Online Library
Protein‐bound uremic toxins (PBUTs) accumulate at high plasma levels and cause various
deleterious effects in end‐stage renal disease patients because their removal by …

Application of nanoparticles as novel adsorbents in blood purification strategies

Y Shen, Y Shen, X Bi, A Shen, Y Wang, F Ding - Blood Purification, 2024 - karger.com
Background: Blood purification therapy for patients overloaded with metabolic toxins or
drugs still needs improvement. Blood purification therapies, such as in hemodialysis or …

Optimization of a liposomal DNase I formulation with an extended circulating half-Life

LC Penaloza Arias, DN Huynh, S Babity… - Molecular …, 2022 - ACS Publications
Drug delivery systems such as liposomes are widely used to stabilize and increase the
plasma half-life of therapeutics. In this article, we have investigated two strategies to …

Liposome-supported peritoneal dialysis in the treatment of severe hyperammonemia: An investigation on potential interactions

G Giacalone, S Matoori, V Agostoni, V Forster… - Journal of controlled …, 2018 - Elsevier
Peritoneal dialysis (PD) performed with transmembrane pH-gradient liposomes was
reported to efficiently remove ammonia from the body, representing a promising alternative …