Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments
Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …
CX3CL1 signaling in the tumor microenvironment
Abstract CX3CL1 (Fractalkine) is a multifunctional inflammatory chemokine with a single
receptor CX3CR1. The biological effects elicited by CX3CL1 on surrounding cells vary …
receptor CX3CR1. The biological effects elicited by CX3CL1 on surrounding cells vary …
Obesity and the risk of gastrointestinal cancers
J Karczewski, B Begier-Krasińska, R Staszewski… - Digestive diseases and …, 2019 - Springer
Obesity is a risk factor for all major gastrointestinal cancers. With the rapid increase in the
prevalence of obesity worldwide, this link could lead to an elevated burden of cancers of the …
prevalence of obesity worldwide, this link could lead to an elevated burden of cancers of the …
The multifactorial effect of obesity on the effectiveness and outcomes of cancer therapies
Epidemiology studies have demonstrated a clear association between obesity and the
development of several distinct malignancies, with excessive visceral adiposity being an …
development of several distinct malignancies, with excessive visceral adiposity being an …
Tissue-resident memory T cells in chronic liver diseases: Phenotype, development and function
Y Li, Z You, R Tang, X Ma - Frontiers in Immunology, 2022 - frontiersin.org
Tissue-resident memory (TRM) T cells are a unique subset of memory T cells that are critical
for the first line of defense against pathogens or antigens in peripheral non-lymphoid tissues …
for the first line of defense against pathogens or antigens in peripheral non-lymphoid tissues …
Real-time ex vivo monitoring of NK cell migration toward obesity-associated oesophageal adenocarcinoma following modulation of CX3CR1
Oesophagogastric adenocarcinomas (OAC) are poor prognosis, obesity-associated cancers
which may benefit from natural killer (NK) cell-based immunotherapies. Cellular …
which may benefit from natural killer (NK) cell-based immunotherapies. Cellular …
Tissue-Resident memory T cells in the Liver—Unique characteristics of local specialists
LM Bartsch, MPS Damasio, S Subudhi, HK Drescher - Cells, 2020 - mdpi.com
T cells play an important role to build up an effective immune response and are essential in
the eradication of pathogens. To establish a long-lasting protection even after a re-challenge …
the eradication of pathogens. To establish a long-lasting protection even after a re-challenge …
Identifying a Novel Role for Fractalkine (CX3CL1) in Memory CD8+ T Cell Accumulation in the Omentum of Obesity-Associated Cancer Patients
The omentum is enriched with pro-inflammatory effector memory CD8+ T cells in patients
with the obesity-associated malignancy, esophagogastric adenocarcinoma (EAC) and we …
with the obesity-associated malignancy, esophagogastric adenocarcinoma (EAC) and we …
[HTML][HTML] Tissue distribution of γδ T cell subsets in oesophageal adenocarcinoma
AM Melo, E Mylod, V Fitzgerald, NE Donlon… - Clinical …, 2021 - Elsevier
The global obesity epidemic is contributing to increased prevalence of diseases fuelled by
chronic inflammation, including cancer. Oesophageal adenocarcinoma (OAC) is an obesity …
chronic inflammation, including cancer. Oesophageal adenocarcinoma (OAC) is an obesity …
Differential effects of dietary versus exercise intervention on intrahepatic MAIT cells and histological features of NAFLD
S Naimimohasses, P O'Gorman, C Wright, D Ni Fhloinn… - Nutrients, 2022 - mdpi.com
Background: Mucosal-associated invariant T (MAIT) cells promote inflammation in obesity
and are implicated in the progression of non-alcoholic fatty liver disease (NAFLD). However …
and are implicated in the progression of non-alcoholic fatty liver disease (NAFLD). However …