The role of inflammation, hypoxia, and opioid receptor expression in pain modulation in patients suffering from obstructive sleep apnea

P Kaczmarski, FF Karuga, B Szmyd, M Sochal… - International Journal of …, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a relatively common disease in the general population.
Besides its interaction with many comorbidities, it can also interact with potentially painful …

REM-OSA as a Tool to Understand Both the Architecture of Sleep and Pathogenesis of Sleep Apnea—Literature Review

FF Karuga, P Kaczmarski, P Białasiewicz… - Journal of Clinical …, 2023 - mdpi.com
Sleep is a complex physiological state, which can be divided into the non-rapid eye
movement (NREM) phase and the REM phase. Both have some unique features and …

BDNF and proBDNF serum protein levels in obstructive sleep apnea patients and their involvement in insomnia and depression symptoms

A Gabryelska, S Turkiewicz, M Ditmer… - Journal of Clinical …, 2022 - mdpi.com
Introduction: Obstructive sleep apnea (OSA) is a disorder that, apart from somatic sequelae,
increases the risk of developing psychiatric conditions. Brain-derived neurotrophic factor …

Circadian clock dysregulation: a potential mechanism of depression in obstructive sleep apnea patients

A Gabryelska, S Turkiewicz, P Kaczmarski… - Translational …, 2024 - nature.com
Obstructive sleep apnea (OSA) is characterized by co-occurrence with affective disorders.
Our study aims to investigate the association of circadian clock gene expressions, and the …

Circadian clock disruptions link oxidative stress and systemic inflammation to metabolic syndrome in obstructive sleep apnea patients

X Li, X Liu, Q Meng, X Wu, X Bing, N Guo… - Frontiers in …, 2022 - frontiersin.org
Objectives: Obstructive sleep apnea (OSA) is an independent risk factor for metabolic
syndrome (MetS). Recent studies have indicated that circadian clock genes were …

Circadian rhythm disruption as a contributor to racial disparities in prostate cancer

SS Dasari, M Archer, NE Mohamed, AK Tewari… - Cancers, 2022 - mdpi.com
Simple Summary African American (AA) men have 2.4 times higher mortality rate due to
prostate cancer than White men in the United States. Evidence implicates circadian rhythm …

Is obstructive sleep apnea a circadian rhythm disorder?

J Šmon, E Kočar, T Pintar… - Journal of sleep …, 2023 - Wiley Online Library
Obstructive sleep apnea is the most common sleep‐related breathing disorder worldwide
and remains underdiagnosed. Its multiple associated comorbidities contribute to a …

Hypoxia induces alterations in the circadian rhythm in patients with chronic respiratory diseases

M Castillejos-López, Y Romero, A Varela-Ordoñez… - Cells, 2023 - mdpi.com
The function of the circadian cycle is to determine the natural 24 h biological rhythm, which
includes physiological, metabolic, and hormonal changes that occur daily in the body. This …

Obstructive sleep apnea, circadian clock disruption, and metabolic consequences

M Malicki, FF Karuga, B Szmyd, M Sochal… - Metabolites, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a chronic disorder characterized by recurrent episodes of
apnea and hypopnea during sleep. It is associated with various cardiovascular and …

[HTML][HTML] Natural Compounds for Preventing Age-Related Diseases and Cancers

MR Ki, S Youn, DH Kim, SP Pack - International Journal of Molecular …, 2024 - mdpi.com
Aging is a multifaceted process influenced by hereditary factors, lifestyle, and environmental
elements. As time progresses, the human body experiences degenerative changes in major …