Affibody molecules are small (6.5-kDa) affinity proteins based on a three-helix bundle
domain framework. Since their introduction 20 years ago as an alternative to antibodies for …

Oncolytic adenovirus therapy is gaining importance as a novel treatment option for the
management of various cancers. Different concepts of modification within the adenovirus …

LOVTRAP is an optogenetic approach for reversible light-induced protein dissociation using
protein A fragments that bind to the LOV domain only in the dark, with tunable kinetics and …

The use of antibody-based therapeutics has proven very promising for clinical applications
in cancer patients, with multiple examples of antibodies and antibody–drug conjugates …

The epidermal growth factor receptor (EGFR) is a cell-surface receptor belonging to ErbB
family of tyrosine kinase and it plays a vital role in the regulation of cell proliferation, survival …

The delivery of drugs through targeted nanocarriers that are internalized by cells provides
an alternative route to diffusion of drugs into cells. Growth factor or vitamin interactions with …

The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap
between single molecules and classical, larger-sized nanomaterials, not only in terms of …

Chemical sensors and biosensors are of increasing interest within the field of modern
analytical chemistry, as can be seen both from the number of papers published and from the …

Red light penetrates deep into mammalian tissues and has low phototoxicity, but few
optogenetic tools that use red light have been developed. Here we present MagRed, a red …