Provably efficient safe exploration via primal-dual policy optimization

D Ding, X Wei, Z Yang, Z Wang… - … conference on artificial …, 2021 - proceedings.mlr.press
We study the safe reinforcement learning problem using the constrained Markov decision
processes in which an agent aims to maximize the expected total reward subject to a safety …

A promising approach to optimizing sequential treatment decisions for depression: Markov decision process

F Li, F Jörg, X Li, T Feenstra - Pharmacoeconomics, 2022 - Springer
The most appropriate next step in depression treatment after the initial treatment fails is
unclear. This study explores the suitability of the Markov decision process for optimizing …

Nonstationary bandits with habituation and recovery dynamics

Y Mintz, A Aswani, P Kaminsky… - Operations …, 2020 - pubsonline.informs.org
Many settings involve sequential decision making where a set of actions can be chosen at
each time step, each action provides a stochastic reward, and the distribution for the reward …

Interpretable policies and the price of interpretability in hypertension treatment planning

GGP Garcia, LN Steimle, WJ Marrero… - … & Service Operations …, 2024 - pubsonline.informs.org
Problem definition: Effective hypertension management is critical to reducing the
consequences of atherosclerotic cardiovascular disease, a leading cause of death in the …

Optimal cholesterol treatment plans and genetic testing strategies for cardiovascular diseases

WJ Marrero, MS Lavieri, JB Sussman - Health Care Management Science, 2021 - Springer
Atherosclerotic cardiovascular disease (ASCVD) is among the leading causes of death in
the US. Although research has shown that ASCVD has genetic elements, the understanding …

Multimodality treatment planning using the Markov decision process: a comprehensive study of applications and challenges

P Singh, S Singh, A Mishra, SK Mishra - Research on Biomedical …, 2024 - Springer
Purpose According to the oncologist, a single medication is insufficient to completely cure
the disease; as a result, most patients undergo treatment from two or more types of therapy …

Personalizing second-line type 2 diabetes treatment selection: combining network meta-analysis, individualized risk, and patient preferences for unified decision …

SE Choi, SA Berkowitz, JS Yudkin… - Medical Decision …, 2019 - journals.sagepub.com
Background. Personalizing medical treatment often requires practitioners to compare
multiple treatment options, assess a patient's unique risk and benefit from each option, and …

An adaptive optimization approach to personalized financial incentives in mobile behavioral weight loss interventions

Q Li, KL Gavin, CI Voils, Y Mintz - arXiv preprint arXiv:2307.00444, 2023 - arxiv.org
Obesity is a critical healthcare issue affecting the United States. The least risky treatments
available for obesity are behavioral interventions meant to promote diet and exercise. Often …

Dynamic treatment selection and modification for personalised blood pressure therapy using a Markov decision process model: a cost-effectiveness analysis

SE Choi, ML Brandeau, S Basu - BMJ open, 2017 - bmjopen.bmj.com
Objective Personalised medicine seeks to select and modify treatments based on individual
patient characteristics and preferences. We sought to develop an automated strategy to …

Examining chronic kidney disease screening frequency among diabetics: a POMDP approach

CC Wu, Y Cao, S Suen, E Lin - Health Care Management Science, 2024 - Springer
Forty percent of diabetics will develop chronic kidney disease (CKD) in their lifetimes.
However, as many as 50% of these CKD cases may go undiagnosed. We developed …