The Adaptive Immune Response against Bunyavirales
R Alatrash, BB Herrera - Viruses, 2024 - mdpi.com
The Bunyavirales order includes at least fourteen families with diverse but related viruses,
which are transmitted to vertebrate hosts by arthropod or rodent vectors. These viruses are …
which are transmitted to vertebrate hosts by arthropod or rodent vectors. These viruses are …
Entry inhibitors as arenavirus antivirals
K Iyer, Z Yan, SR Ross - Frontiers in Microbiology, 2024 - frontiersin.org
Arenaviruses belonging to the Arenaviridae family, genus mammarenavirus, are enveloped,
single-stranded RNA viruses primarily found in rodent species, that cause severe …
single-stranded RNA viruses primarily found in rodent species, that cause severe …
Characterization of bi-segmented and tri-segmented recombinant Pichinde virus particles
H Murphy, Q Huang, J Jensen, N Weber… - Journal of …, 2024 - journals.asm.org
Mammarenaviruses include several highly virulent pathogens (eg, Lassa virus) capable of
causing severe hemorrhagic fever diseases for which there are no approved vaccines and …
causing severe hemorrhagic fever diseases for which there are no approved vaccines and …
A Lassa virus live attenuated vaccine candidate that is safe and efficacious in guinea pigs
Lassa virus (LASV) is a rodent-borne mammarenavirus that causes tens to hundreds of
thousands of human infections annually in Western Africa. Approximately 20% of these …
thousands of human infections annually in Western Africa. Approximately 20% of these …
[HTML][HTML] Development of Effective Medical Countermeasures Against the Main Biowarfare Agents: The Importance of Antibodies
A Avril, S Guillier, C Rasetti-Escargueil - Microorganisms, 2024 - mdpi.com
The COVID-19 and mpox crisis has reminded the world of the potentially catastrophic
consequences of biological agents. Aside from the natural risk, biological agents can also …
consequences of biological agents. Aside from the natural risk, biological agents can also …
[HTML][HTML] Strategies of rational and structure-driven vaccine design for Arenaviruses
The COVID-19 outbreak has highlighted the importance of pandemic preparedness for the
prevention of future health crises. One virus family with high pandemic potential are …
prevention of future health crises. One virus family with high pandemic potential are …
[HTML][HTML] Evaluating Antigen-and Vector-Specific Immune Responses of a Recombinant Pichinde Virus-Based Vaccine Expressing the Lymphocytic Choriomeningitis …
Background: Live viral vector-based vaccines are known to elicit strong immune responses,
but their use can be limited by anti-vector immunity. Here, we analyzed the immunological …
but their use can be limited by anti-vector immunity. Here, we analyzed the immunological …
Immunoinformatic based designing of highly immunogenic multi-epitope subunit vaccines to stimulate an adaptive immune response against Junin virus
Abstract The Junin virus causes Argentine hemorrhagic fever, leading to severe
complications such as high fever, malaise, muscle pain, and bleeding disorders, including …
complications such as high fever, malaise, muscle pain, and bleeding disorders, including …
[HTML][HTML] Exploring Future Pandemic Preparedness Through the Development of Preventive Vaccine Platforms and the Key Roles of International Organizations in a …
J Jeon, E Kim - Vaccines, 2025 - mdpi.com
Background: The emergence of more than 40 new infectious diseases since the 1980s has
emerged as a serious global health concern, many of which are zoonotic. In response, many …
emerged as a serious global health concern, many of which are zoonotic. In response, many …
[PDF][PDF] Entry inhibitors as arenavirus
K Iyer, Z Yan, SR Ross - 2024 - researchgate.net
New and Old World arenaviruses belong to the Arenaviridae family, genus Mammarenavirus
(Grande-Pérez et al., 2016; Hallam et al., 2018; Garry, 2023). Many cause severe …
(Grande-Pérez et al., 2016; Hallam et al., 2018; Garry, 2023). Many cause severe …