The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

S Krasemann, U Haferkamp, S Pfefferle, MS Woo… - Stem cell reports, 2022 - cell.com
Neurological complications are common in COVID-19. Although SARS-CoV-2 has been
detected in patients' brain tissues, its entry routes and resulting consequences are not well …

Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection

SF Martins Gomes, AJ Westermann… - Frontiers in …, 2019 - frontiersin.org
Meningococcal meningitis is a severe central nervous system infection that occurs when
Neisseria meningitidis (Nm) penetrates brain endothelial cells (BECs) of the meningeal …

Human-Induced Pluripotent Stem Cell-Based Model of the Blood-Brain at 10 Years: A Retrospective on Past and Current Disease Models

AJ Al-Ahmad - Human iPSC-derived Disease Models for Drug …, 2023 - Springer
The initial discovery and derivation of induced pluripotent stem cells (iPSCs) by Yamanaka
and colleagues in 2006 revolutionized the field of personalized medicine, as it opened the …

Induced Pluripotent Stem Cell (iPSC)-Derived Endothelial Cells to Study Bacterial–Brain Endothelial Cell Interactions

ER Espinal, SJ Sharp, BJ Kim - The Blood-Brain Barrier: Methods and …, 2022 - Springer
Bacterial meningitis is a serious infection of the central nervous system (CNS) that occurs
when blood-borne bacteria are able to exit the cerebral vasculature and cause inflammation …

Neisseria meningitidis infection of induced pluripotent stem-cell derived brain endothelial cells

LM Endres, SF Hathcock, A Schubert-Unkmeir… - JoVE (Journal of …, 2020 - jove.com
Meningococcal meningitis is a life-threatening infection that occurs when Neisseria
meningitidis (meningococcus, Nm) can gain access to the central nervous system (CNS) by …

Development of a multicellular in vitro model of the meningeal blood-CSF barrier to study Neisseria meningitidis infection

LM Endres, M Jungblut, M Divyapicigil, M Sauer… - Fluids and Barriers of …, 2022 - Springer
Background Bacterial meningitis is a life-threatening disease that occurs when pathogens
such as Neisseria meningitidis cross the meningeal blood cerebrospinal fluid barrier …

Interactions and Signal Transduction Pathways Involved during Central Nervous System Entry by Neisseria meningitidis across the Blood–Brain Barriers

J Borkowski, H Schroten, C Schwerk - International Journal of Molecular …, 2020 - mdpi.com
The Gram-negative diplococcus Neisseria meningitidis, also called meningococcus,
exclusively infects humans and can cause meningitis, a severe disease that can lead to the …

Genetic dynamics of invasive Neisseria meningitidis strains in Portugal

CR Bettencourt - 2022 - search.proquest.com
Neisseria meningitidisis a strictly human bacteria, often present in the human
nasopharyngeal microbiota that occasionally cause life-threatening infections, including …

Natural Animal Models to Study Neisserial Asymptomatic Colonization and Persistence

E Thapa - 2022 - rave.ohiolink.edu
Members of the genus Neisseria are common mucosal commensals of animals and
humans. Two species, Neisseria meningitidis and Neisseria gonorrhoeae cause diseases …

[PDF][PDF] 10University Hospital Würzburg, Chair Tissue Engineering and Regenerative Medicine (TERM), 97070 Würzburg, Germany 11Fraunhofer Institute for Silicate …

S Krasemann, U Haferkamp, S Pfefferle, MS Woo - researchgate.net
Neurological complications are common in COVID-19. Although SARS-CoV-2 has been
detected in patients' brain tissues, its entry routes and resulting consequences are not well …