2011-05-19 Assigned to INTELLIKINE, INC. reassignment INTELLIKINE, INC. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: REN, PINGDA …

Introduction: The p90 ribosomal S6 kinases (RSK) are a family of Ser/Thr protein kinases
that are downstream effectors of MEK1/2-ERK1/2. Increased RSK activation is implicated in …

The present invention relates to novel kinase inhibitors and modulator compounds useful for
the treatment of various diseases. More particularly, the invention is concerned with Such …

0 [1*] N ([2*]) c1ccn ([6*]) c2c1C (= O) n ([3*]) cc2 ([4*])[5*] Chemical compound [1*] N ([2*])
c1ccn ([6*]) c2c1C (= O) n ([3*]) cc2 ([4*])[5*] 0.000 description 44XWBZYQSNBZOEQQ …

US8476431B2 - Benzoxazole kinase inhibitors and methods of use - Google Patents
US8476431B2 - Benzoxazole kinase inhibitors and methods of use - Google Patents …

US8993580B2 - Benzothiazole kinase inhibitors and methods of use - Google Patents
US8993580B2 - Benzothiazole kinase inhibitors and methods of use - Google Patents …

2014-10-10 Assigned to CELGENE AVILOMICS RESEARCH, INC. reassignment CELGENE
AVILOMICS RESEARCH, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

(63) Continuation of application No. 14/139,723, filed on DE 2004713 A1 8/1971 Dec. 23,
2013, now abandoned, which is a EP O773O23 A1 5, 1997 continuation of application No …

The invention features compounds, pharmaceutical compo sitions and methods for treating
patients who have an EGFR-driven cancer of formula I:(52) Int. Cl. C07D 239/46(2006. 01) …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
41340562&utm_source= google_patent&utm_medium= platform_link&utm_campaign …