Hepatocellular carcinoma in chronic viral hepatitis: where do we stand?

FP Russo, A Zanetto, E Pinto, S Battistella… - International journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death.
Although the burden of alcohol-and NASH-related HCC is growing, chronic viral hepatitis …

Targeted therapy for hepatocellular carcinoma: old and new opportunities

C Laface, P Fedele, FM Maselli, F Ambrogio, C Foti… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the most frequent primitive cancer of
the liver, accounting for 90% of all recorded cases. HCC is the third most common cause of …

[HTML][HTML] Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study

CAM Fulgenzi, J Cheon, A D'Alessio, N Nishida… - European Journal of …, 2022 - Elsevier
Background IMbrave150 has established the superiority of atezolizumab plus bevacizumab
over sorafenib in patients with unresectable hepatocellular carcinoma (HCC). Methods We …

The systemic inflammatory response identifies patients with adverse clinical outcome from immunotherapy in hepatocellular carcinoma

A Muhammed, CAM Fulgenzi, S Dharmapuri, M Pinter… - Cancers, 2021 - mdpi.com
Simple Summary The investigation of predictive and prognostic markers is pivotal in patients
affected by hepatocellular carcinoma treated with immune-checkpoint-inhibitors …

Real-world study of hepatic artery infusion chemotherapy combined with anti-PD-1 immunotherapy and tyrosine kinase inhibitors for advanced hepatocellular …

BJ Liu, S Gao, X Zhu, JH Guo, FX Kou, SX Liu… - …, 2021 - Taylor & Francis
Aim: We investigated the efficacy and safety of hepatic artery infusion chemotherapy (HAIC)
combined with anti-PD-1 immunotherapy and tyrosine kinase inhibitors (TKIs) for advanced …

Progression patterns and therapeutic sequencing following immune checkpoint inhibition for hepatocellular carcinoma: an international observational study

T Talbot, A D'Alessio, M Pinter, L Balcar… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Different approaches are available after the progression of
disease (PD) to immune checkpoint inhibitors (ICIs) for hepatocellular carcinoma (HCC) …

The new era of systemic treatment for hepatocellular carcinoma: from the first line to the optimal sequence

M Cerreto, F Cardone, L Cerrito, L Stella… - Current …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) represents the most common primary liver cancer and is
considered a major global health problem as one of the leading causes of cancer-related …

Immunotherapies for advanced hepatocellular carcinoma

LY Sun, KJ Zhang, YM Xie, JW Liu… - Frontiers in …, 2023 - frontiersin.org
Primary liver cancer is the second leading cause of tumor-related deaths in China, with
hepatocellular carcinoma (HCC) accounting for 80%–90% of these. Since there is a lack of …

Current insights into the hepatic microenvironment and advances in immunotherapy for hepatocellular carcinoma

M Zhao, H Huang, F He, X Fu - Frontiers in Immunology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and shows
high global incidence and mortality rates. The liver is an immune-tolerated organ with a …

[HTML][HTML] Integrated analysis of expression, prognostic value and immune infiltration of GSDMs in hepatocellular carcinoma

K Hu, Z Xu, L Yao, Y Yan, L Zhou, J Li - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Six Gasdermins (GSDM) family members participate in various biological processes
especially pyroptosis, as well as in the initiation and development of many types of cancer …