Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier

DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …

Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease

B Fonseca-Santos, MPD Gremião… - International Journal of …, 2015 - Taylor & Francis
Alzheimer's disease is a neurological disorder that results in cognitive and behavioral
impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs …

Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges

MM Wen, NS El-Salamouni, WM El-Refaie… - Journal of controlled …, 2017 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease with high prevalence in the
rapidly growing elderly population in the developing world. The currently FDA approved …

Nano carrier drug delivery systems for the treatment of neuropsychiatric disorders: Advantages and limitations

Y Zorkina, O Abramova, V Ushakova, A Morozova… - Molecules, 2020 - mdpi.com
Neuropsychiatric diseases are one of the main causes of disability, affecting millions of
people. Various drugs are used for its treatment, although no effective therapy has been …

Titanium dioxide food additive (E171) induces ROS formation and genotoxicity: contribution of micro and nano-sized fractions

H Proquin, C Rodríguez-Ibarra, CGJ Moonen… - …, 2017 - academic.oup.com
Abstract Since 1969, the European Union approves food-grade titanium dioxide (TiO2), also
known as E171 colouring food additive. E171 is a mixture of micro-sized particles (MPs) and …

Phyto-therapeutic and nanomedicinal approaches to cure Alzheimer's disease: present status and future opportunities

M Ovais, N Zia, I Ahmad, AT Khalil, A Raza… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is characterized by cognitive inability manifested due to the
accumulation of β-amyloid, formation of hyper phosphorylated neurofibrillary tangles, and a …

Lipid-based nanocarriers for neurological disorders: a review of the state-of-the-art and therapeutic success to date

BA Witika, MS Poka, PH Demana, SK Matafwali… - Pharmaceutics, 2022 - mdpi.com
Neurodegenerative disorders including Alzheimer's, Parkinson's, and dementia are chronic
and advanced diseases that are associated with loss of neurons and other related …

Nano-carrier enabled drug delivery systems for nose to brain targeting for the treatment of neurodegenerative disorders

S Md, SK Bhattmisra, F Zeeshan, N Shahzad… - Journal of Drug Delivery …, 2018 - Elsevier
A major hurdle for the treatment of neurodegenerative disorders is the inability of drug
molecules to cross the blood-brain barrier (BBB). Many anti-Parkinson and anti-Alzheimer …

Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease

B Ray, B Maloney, K Sambamurti, HK Karnati… - Translational …, 2020 - nature.com
Rivastigmine (or Exelon) is a cholinesterase inhibitor, currently used as a symptomatic
treatment for mild-to-moderate Alzheimer's disease (AD). Amyloid-β peptide (Aβ) generated …

Clitoria ternatea Mediated Synthesis of Graphene Quantum Dots for the Treatment of Alzheimer's Disease

K Tak, R Sharma, V Dave, S Jain… - ACS Chemical …, 2020 - ACS Publications
The main purpose of the present study was to synthesize graphene quantum dots (GQDs)
from the flowers of Clitoria ternatea with the help of one-pot microwave-assisted green …