Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression
AA Grace - Nature Reviews Neuroscience, 2016 - nature.com
The dopamine system is unique among the brain's modulatory systems in that it has discrete
projections to specific brain regions involved in motor behaviour, cognition and emotion …
projections to specific brain regions involved in motor behaviour, cognition and emotion …
Reactive astrocytes as neural stem or progenitor cells: in vivo lineage, in vitro potential, and genome‐wide expression analysis
M Götz, S Sirko, J Beckers, M Irmler - Glia, 2015 - Wiley Online Library
Here, we review the stem cell hallmarks of endogenous neural stem cells (NSCs) during
development and in some niches of the adult mammalian brain to then compare these with …
development and in some niches of the adult mammalian brain to then compare these with …
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays
Spatially resolved transcriptomic technologies are promising tools to study complex
biological processes such as mammalian embryogenesis. However, the imbalance between …
biological processes such as mammalian embryogenesis. However, the imbalance between …
Fused cerebral organoids model interactions between brain regions
Human brain development involves complex interactions between different regions,
including long-distance neuronal migration or formation of major axonal tracts. Different …
including long-distance neuronal migration or formation of major axonal tracts. Different …
A survey of human brain transcriptome diversity at the single cell level
The human brain is a tissue of vast complexity in terms of the cell types it comprises.
Conventional approaches to classifying cell types in the human brain at single cell …
Conventional approaches to classifying cell types in the human brain at single cell …
Genetic reduction of matrix metalloproteinase-9 promotes formation of perineuronal nets around parvalbumin-expressing interneurons and normalizes auditory cortex …
TH Wen, S Afroz, SM Reinhard, AR Palacios… - Cerebral …, 2018 - academic.oup.com
Abnormal sensory responses associated with Fragile X Syndrome (FXS) and autism
spectrum disorders include hypersensitivity and impaired habituation to repeated stimuli …
spectrum disorders include hypersensitivity and impaired habituation to repeated stimuli …
A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients
Dravet Syndrome is an intractable form of childhood epilepsy associated with deleterious
mutations in SCN1A, the gene encoding neuronal sodium channel Nav1. 1. Earlier studies …
mutations in SCN1A, the gene encoding neuronal sodium channel Nav1. 1. Earlier studies …
Gabaergic interneurons in early brain development: conducting and orchestrated by cortical network activity
D Warm, J Schroer, A Sinning - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Throughout early phases of brain development, the two main neural signaling mechanisms—
excitation and inhibition—are dynamically sculpted in the neocortex to establish primary …
excitation and inhibition—are dynamically sculpted in the neocortex to establish primary …
Correspondence between resting-state activity and brain gene expression
The relationship between functional brain activity and gene expression has not been fully
explored in the human brain. Here, we identify significant correlations between gene …
explored in the human brain. Here, we identify significant correlations between gene …
Involvement of cortical fast-spiking parvalbumin-positive basket cells in epilepsy
X Jiang, M Lachance, E Rossignol - Progress in brain research, 2016 - Elsevier
GABAergic interneurons of the parvalbumin-positive fast-spiking basket cells subtype (PV
INs) are important regulators of cortical network excitability and of gamma oscillations …
INs) are important regulators of cortical network excitability and of gamma oscillations …