Testosterone is essential for maintaining spermatogenesis and male fertility. However, the
molecular mechanisms by which testosterone acts have not begun to be revealed until …

Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in
regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited …

Male factor infertility is increasing in developed countries, and several factors linked to
lifestyle have been shown to negatively affect spermatogenesis. Sertoli cells are pivotal to …

Spermatogenesis and male fertility are dependent upon the presence of testosterone in the
testis. In the absence of testosterone or the androgen receptor, spermatogenesis does not …

Spermatogenesis is completely dependent on the pituitary hormone follicle-stimulating
hormone (FSH) and androgens locally produced in response to luteinising hormone (LH) …

Testosterone and follicle-stimulating hormone (FSH) are required to obtain full reproductive
potential. In the testis, somatic Sertoli cells transduce signals from testosterone and FSH into …

Testosterone is essential to maintain spermatogenesis and male fertility. In the absence of
testosterone stimulation, spermatogenesis does not proceed beyond the meiosis stage. After …

Hormonal regulation is essential to spermatogenesis. Sertoli cells (SCs) have functions that
reach far beyond the physical support of germ cells, as they are responsible for creating the …

Testosterone is essential for spermatogenesis and male fertility. In this review, topics related
to testosterone control of spermatogenesis are covered including testosterone production …

Male infertility contributes to 50% of all cases of infertility. The main cause is low quality and
quantity of sperm. In humans, spermatogenesis starts at the beginning of puberty and lasts …