Methicillin-resistant Staphylococcus aureus (MRSA), as a classic reason for genuine skin
and flimsy tissues diseases, is a worldwide general wellbeing risk and has already …

Oxazolidinone is a five-member heterocyclic ring with several biological applications in
medicinal chemistry. Among the three possible isomers, 2-oxazolidinone is the most …

O‐Heterocycles have been explored in the field of medicinal chemistry for a long time, but
their significance has not been duly recognised and they are often shunned in favour of N …

TB drug development pipeline represents varied structural classes of molecules.
Oxazolidinones represent synthetic anti-bacterial agents with unique mechanism of action …

Tuberculosis (TB) is an infectious and fatal disease caused by Mycobacterium tuberculosis
(Mtb) and remains a serious public health threat; therefore, the development of new …

Tuberculosis (TB) remains a significant global health challenge, with “multidrug-resistant
(MDR-TB) and extensively drug-resistant (XDR-TB) strains” posing severe threats to …

Pyrimidine-1, 3-oxazolidin-2-arylimino hybrids have been synthesized as a new class of
antibacterial agents. The synthetic approach exploits a Cu (II)-catalyzed intramolecular …

Oxazolidinones are a novel class of synthetic antibacterial agents that inhibit bacterial
protein synthesis. Here, we synthesized and tested a series of oxazolidinone compounds …

This thesis by publication compares computational methods to analyze an untested dataset
of oxazolidinones, a type of antibacterials that target ribosomes. The study evaluates …

US10052306B2 - Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B -
Google Patents US10052306B2 - Selective octahydro-cyclopenta[C] pyrrole negative …