Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome associated
with poor quality of life, substantial health-care resource utilization, and premature mortality …

Background Diabetes and elevated blood glucose have been associated with increased risk
of atrial fibrillation in a number of epidemiological studies, however, the findings have not …

Background: Higher androgen and lower estrogen levels are associated with cardiovascular
disease (CVD) risk factors in women. However, studies on sex hormones and incident CVD …

Background: Lower leisure-time physical activity (LTPA) and higher body mass index (BMI)
are independently associated with risk of heart failure (HF). However, it is unclear if this …

Importance Despite the importance of age, sex, and race/ethnicity representativeness in
clinical trials, limited data exist regarding the enrollment trends of these groups in …

Background: Lifetime risk of heart failure has been estimated to range from 20% to 46% in
diverse sex and race groups. However, lifetime risk estimates for the 2 HF phenotypes, HF …

Background Heart failure (HF) is a major driver of health care costs in the United States and
is increasing in prevalence. There is a paucity of contemporary data examining trends …

An increasing number of studies clearly demonstrate that coronary microvascular
dysfunction (CMD) plays a pivotal role in several cardiovascular diseases. 1 In particular …

Background: Inflammation may play a role in the pathophysiology of heart failure with
preserved ejection fraction. We examined whether circulating levels of interleukin-6 identify …

Abstract Purpose of Review Heart failure with preserved ejection fraction (HFpEF) is a
relatively new disease entity used in medical terminology; however, both the number of …